Name Contact Programs Research Interest
Jennifer Adibi MPH, ScD
Program 1: Epidemiology
Program 2:
Susanne Ahmari, MD, PhD
Program 1: Neuroscience (CNUP)
Circuit dynamics underlying pathology and treatment of compulsive behaviors and anxiety disorder
Jinwoo Ahn, PhD
Program 2:
Functional and structural studies of HIV accessory proteins and their human cellular partners;SAMHD1 dual enzyme activities
Rannar Airik, PhD
airikr@pitt.edu Molecular mechanisms of chronic kidney disease. DNA damage induced kidney senescence. Molecular regulation of kidney injury and fibrosis. Cystic kidney disease. Ciliary signaling and Ciliopathies
Elias Aizenman, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Cellular and Molecular Basis of Neurodegeneration
Howard Aizenstein, MD, PhD
Program 1: Bioengineering
Program 2: Neuroscience (CNUP)
Our lab uses structural and functional MRI to study the brain changes associated with aging, and the disorders of aging
Kathryn Albers, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Growth factor and transcriptional regulation of neuronal function in pain and disease.
Gerard Apodaca, PhD
gla6@pitt.edu Endocytic pathways and stretch-regulated endocytosis/exocytosis in bladder.
Bruce Armitage, PhD
Program 2:
Bioorganic Chemistry, Fluorescent Dyes, DNA Nanotechnology, Molecular Evolution, Peptide Nucleic Acids, Molecular Recognition of DNA/RNA, G Quadruplexes
Stephen Badylak, MD, PhD
Program 1: Bioengineering
Tissue Engineering and Regenerative Medicine, emphasis upon clinical application; cell:biomaterial interactions; epimorphic regeneration in mammals
Ivet Bahar, PhD
bahar@pitt.edu Biomolecular systems dynamics; computer-aided drug discovery; network models for protein-protein interactions.
Christopher Bakkenist, PhD
Program 2:
Identify phosphorylations, dephosphorylations and acetylations that regulate ATM activity in vivo.
Alison Barth, PhD
albarth@andrew.cmu.edu The organization and plasticity of neocortical circuits in rodents.
Carl Bates, MD
Program 2:
Interrogates the roles of fibroblast growth factor receptors and their adapters in kidney and lower urinary tract development.
Aaron Batista, PhD
Program 1: Bioengineering
Neurophysiology of sensory-motor coordination, brain-machine interfaces.
Hulya Bayir, MD
Program 2:
Lipid signaling and lipid imaging in cell death and inflammation. Mitochondrial injury and mitochondria - targeted therapies. Redox biomedicine
Marlene Behrmann, PhD
Program 1: Neuroscience (CNUP)
Program 2: Psychology (CMU)
Interdisciplinary approach to explore how the signals from the eye are transformed into meaningful percepts by the brain
Takis Benos, PhD
Program 2:
Our ultimate goal is to investigate the molecular mechanisms of chronic diseases and cancer and develop predictive methods and tools that will improve health.
Sarah Berman, MD, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Role of mitochondrial dynamics in Parkinson’s disease and other neurodegenerative diseases
Kara Bernstein, PhD
Program 2:
Repair of DNA damage is crucial to prevent mutations observed in cancer. Using live cell imaging, we study how double-strand breaks are repaired.
Timothy Billiar, MD
Program 2:
The Billiar Lab focuses on the immune responses to acute systemic stresses of major clinical relevance including trauma and surgical sepsis
Robert Binder, PhD
Program 2:
The mechanisms of cross-priming of antigens during immune responses to cancer, viruses and autoimmunity
David Binion, MD
biniond@upmc.edu Defining the cellular and molecular mechanisms underlying human chronic gut inflammation and the translation of this knowledge into improved care for patients suffering from Crohn’s disease and ulcerative colitis.
Jennifer Bomberger, PhD
Program 2:
Understanding the molecular mechanisms for viral-bacterial synergy in the lungs of chronic lung disease patients
Lisa Borghesi, PhD
Program 2:
Demand adapted hematopoiesis in infection and inflammation.
Harvey Borovetz, PhD
Program 1: Bioengineering
Program 2:
Cardiovascular organ replacements for adult and pediatric patients.
Richard Boyce, PhD
Program 2:
Informatics interventions to improve medication safety, especially for older adults; Structured publishing of biomedical knowledge and data
Jeffrey Brodsky, PhD
jbrodsky@pitt.edu Protein “quality control”, diseases associated with misfolded proteins, and drug treatments for these diseases
Ronald Buckanovich, MD, PhD
rjb101@pitt.edu Tumor microenvironment, Cancer stem cells, novel therapeutics for cancer
Timothy Burns, MD, PhD
Program 2:
Development of targeted therapies for KRAS mutant NSCLC; Reactivation of OIS and apoptosis; Mechanisms of acquired resistance to targeted agents
Edward Burton, MD, DPhil
Program 1: Neuroscience (CNUP)
Program 2:
Analysis of the molecular pathogenesis of neurological diseases using viral gene transfer and novel zebrafish models
Michael Butterworth, PhD
Program 2:
Investigating the role of non-coding RNAs in the hormonal regulation of ion transport. Salt and water balance in the mammalian kidney and human airway.
Carlos Camacho, PhD
Program 2:
Computational drug discovery
Anne-Ruxandra Carvunis, PhD
Program 2:
In the Carvunis lab, we study the molecular mechanisms of change and innovation in evolution.
Jane Cauley, DrPH
Program 1: Epidemiology
Program 2:
Osteoporosis treatment and the consequences of osteoporosis in both men and women.
Stephen Chan, MD, PhD
Program 2:
basic science and translational research studying the molecular mechanisms of pulmonary vascular disease and pulmonary hypertension
Yuan Chang, MD
yc70@pitt.edu The study of human tumor viruses
Gretchen Chapman, PhD
Program 2:
Dr. Chapman’s research goal is to illuminate the psychological processes underlying decision making & to harness these findings in the design of theoretically-motivated, policy-relevant interventions to facilitate healthy & prosocial behavior.
Jun Chen, MD, PhD
Program 1: Neuroscience (CNUP)
Mechanisms of cell death and neuroprotection in cerebral ischemia and Parkinson's disease.
Charleen Chu, MD, PhD
Program 2: Neuroscience (CNUP)
Redox signaling & autophagy in neuroprotection and neurodegeneration; mitochondrial phosphoproteomics; genetic & toxin models of Parkinson's disease
Lan Coffman, MD, PhD
Marlene Cohen, PhD
Program 1: Neuroscience (CNUP)
Program 2:
My group studies the way visual information is encoded in groups of neurons and used to guide behavior.
Carol Colby, PhD
Program 1: Neuroscience (CNUP)
Professor Colby's research is on neural mechanisms of spatial cognition, it encompasses a wide range of cognitive processes, including perception, attention, working memory, and the generation of action
James Conway, PhD
Program 2:
Structure and function of virus capsids using cryo-electron microscopy; combine with subunit atomic models to examine interfaces.
Keith Cook, PhD
Program 2:
Artificial lungs; hemodynamics, pulmonary drug delivery; liquid ventilation; right ventricular function, critical care medicine
Vaughn Cooper, PhD
vaughn.cooper@pitt.edu To understand how bacteria adapt to new environments and/or cause disease. Biofilm-associated infections are our primary focus.
Louise D'Cruz, PhD
Program 2:
The D’Cruz lab focuses on how innate and adaptive effector T cells respond to infectious agents.
Lance Davidson, PhD
Program 1: Bioengineering
Our group combines experimental and theoretical approaches to reverse-engineer the inherently mechanical processes of cell and tissue development.
Brian Davis, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Cellular and molecular mechanisms of central and peripheral nervous system development and plasticity
Marie DeFrancis, MD, PhD
Program 2:
HGF-MET-PI3K signaling in liver development, growth, regeneration and cancer. She has identified a novel regulator of the catalytic subunit of PI3K (p110) called PI3K interacting protein 1 (PIK3IP1)
Donald DeFranco, PhD
Program 2: Neuroscience (CNUP)
Steroid hormone action in neural stem cells and cancer
Howard Degenholtz, PhD
Program 2:
Long-term care and aging, bioethics, and organ donation.
Alex Deiters, PhD
Program 1: Chemistry
Development of chemical tools to explore disease-relevant biological questions, with a focus on optical and small molecule control of cell function
Greg Delgoffe, PhD
Program 2:
The metabolic regulation of T cell function, with a specific focus of those T cells that infiltrate the nutrient-poor tumor microenvironment.
Neal DeLuca, PhD
ndeluca@pitt.edu HSV gene expression in productive and persistent infections
Terry Dermody, MD
terence.dermody@chp.edu Research in the Dermody laboratory focuses on the molecular mechanisms of Mammalian Orthoreovirus (reovirus) and Chikungunya virus infections.
Berthony Deslouches, MD, PhD
Program 2:
Mary Amanda Dew, PhD
Program 2: Epidemiology
Behavioral mental health and quality of life outcomes in end-stage organ disease, transplantation, and living donation; research methodology
Thomas Diacovo, MD
Edward Dixon, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Mechanisms of post-traumatic memory deficits, models of traumatic brain injury, and functional outcomes.
Brent Doiron, PhD
Program 2:
General research program seeks to identify how single neurons and networks of neurons code information about relevant inputs.
Julie Donohue, PhD
Program 2:
Conducts research in the areas of pharmaceutical policy and mental health, and has particular expertise in the Affordable Care Act.
Julie S. Downs, PhD
downs@cmu.edu Social influences on decision making; Behavioral intervention to improve risky decisions
Andrew Duncan, PhD
Program 2:
Research in the Duncan lab focuses on liver development, homeostasis and regeneration.
Mo Ebrahimkhani, M.D.
mo.ebr@pitt.edu Programming stem cell morphogenesis with synthetic and systems biology, Human organoids, CRISPR based epigenetic modulation, Translational applications of organoids in liver and hematopoietic systems for disease modeling and regenerative therapies
James Faeder, PhD
faeder@pitt.edu My lab is interested in developing mathematical models of biological regulatory processes that integrate specific knowledge about protein-protein interactions.
Fabio Fararelli, MD, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Neurobiology of psychosis and schizophrenia; Sleep regulation in health and disease; Neuroplasticity and non-invasive brain stimulation
William Federspiel, PhD, MS
Program 1: Bioengineering
Program 2:
Respiratory assist and blood processing devices for critical care medicine. Cardiovascular and pulmonary transport phenomena.
Adam Feinberg, PhD
Program 2:
We develop materials-based, engineering strategies to control the self-organization and assembly of various cell types into tissues using nanoscale fabrication and 3D bioprinting. Understanding of higher-order function in biological systems.
Andrew Feranchak, MD
Robert Ferris, MD, PhD
Program 2:
Mechanisms of immune escape and clinical translation to therapeutic cancer immunotherapy trials
Julie Fiez, PhD
Program 1: Neuroscience (CNUP)
Cognitive and educational neuroscience of reading, language, math, and learning.
Michael Fine, MD, MSc
Program 2:
Ways to improve the quality of medical care for patients with common medical problems
Toren Finkel, MD, PhD
Program 2:
aging, metabolism, mitochondria
Kenneth Fish, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Functional consequences of altered connectivity in schizophrenia; the early secretory pathway’s role in neurodevelopment and synaptogenesis
JoAnne Flynn, PhD
Program 2:
Immunology and Pathogenesis of Tuberculosis.
Bruce Freeman, PhD
Program 2:
The production and signal transduction properties of oxidizing and free radical mediators in metabolic, respiratory and cardiovascular diseases.
James Funderburgh, PhD
jlfunder@pitt.edu Stem cells and stem cell therapy, wound healing, tissue regeneration, biological roles of extracellular matrix
Neeraj Gandhi, PhD
Program 1: Neuroscience (CNUP)
Neural basis of sensorimotor integration and cognition
Shou-Jiang Gao, PhD
gaos8@upmc.edu Kaposi’s sarcoma-associate herpesvirus (KSHV), AIDS-related malignancies, Cancer metabolism, Angiogenesis, Innate immunity, Microbiota, microRNAs, Genomics Epigenetics, RNA epigenetics, high-throughput screening (drug and genomic), systems biology
Hartmut Geyer, PhD
Program 2:
Principles of legged dynamics and control, their relation to human motor control, and resulting applications in rehabilitation technology
Arjumand Ghazi, PhD
ARJUMAND.GHAZI@CHP.EDU Genetics of aging, reproduction, lipid metabolism, immunity, protein homeostasis, age-related disease biology
Aryn Gittis, PhD
Program 2: Neuroscience (CNUP)
Neural circuits in the basal ganglia involved in motor control and disease
Mark Gladwin, MD
Program 1: Bioengineering
Program 2:
Biophysical and biochemical measures and mouse models to investigate a novel therapeutic intervention for carbon monoxide poisoning
Eric Goetzman, PhD
Program 1: Human Genetics
Program 2:
Michael Gold, PhD
Program 1: Neuroscience (CNUP)
Program 2:
A translational approach used to study peripheral mechanisms of pain
Vanathi Gopalakrishnan, PhD
vanathi@pitt.edu Predictive modeling for disease classification and biomarker discovery using novel machine learning and knowledge-based approaches
Anthony Grace, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Neurophysiology of basal ganglia system related to psychiatric disorders.
Steven Graham, MD, PhD
Program 1: Neuroscience (CNUP)
Program 2:
How gene expression and activity control cell death in neurons subjected to anoxia, ischemia and other insults.
Angela Gronenborn, PhD
amg100@pitt.edu Combining NMR spectroscopy w/Biophysics, Biochem&Chem to investigate cellular processes at the molecular & atomic levels in relation to human disease
Jeff Gross, PhD
grossjm@pitt.edu Our research focuses on vertebrate eye development, disease modeling and regeneration utilizing the zebrafish as a model system.
Timothy Hand, PhD
Program 2:
Understand the causes of diseases with disruptions between immune system and the microbiota, such as Crohn’s Disease and Environmental Enteropathy.
Lee Harrison, MD
Program 1: Epidemiology
Program 2:
Epidemiology and molecular epidemiology of bacterial pathogens; Epidemiology and prevention of HIV infection in Brazil
Teresa Hastings, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Oxidative mechanisms associated with neurodegeneration.
Graham Hatfull, PhD
gfh@pitt.edu The Hatfull lab in the Department of Biological Sciences at the University of Pittsburgh studies the molecular genetics of the mycobacteria and their mycobacteriophages.
Vicki Helgeson, PhD
Program 1: Psychology (CMU)
Program 2:
implications of gender personality and social environmental variables for how people adjust to chronic illness
Andrew Hinck, PhD
Program 2:
Studying signaling proteins and receptors of the TGF-beta family, deciphering the molecular adaptations that the signaling proteins, single-pass transmembrane receptors, downstream effectors, and multitude of extracellular and intracellular modulators.
Jackie Ho, MD
jacqueline.ho2@chp.edu Chronic kidney disease (CKD) is a growing public health burden that results in significant morbidity and increased risk of mortality for individual patients.
Lori Holt, PhD
Program 1: Psychology (CMU)
Program 2: Neuroscience (CNUP)
My lab investigates the cognitive and neurobiological bases of how human listeners use sound. This involves study of speech communication, auditory perception, attention, and learning.
Gregg Homanics, PhD
Program 2: Neuroscience (CNUP)
Understanding the molecular mechanism(s) of action of alcohol.
John Horn, PhD
Program 1: Neuroscience (CNUP)
Synaptic Computation and Neuromodulation in Catecholaminergic Neurons; Nicotinic receptors; G-protein coupled receptors
Neil Hukriede, PhD
hukriede@pitt.edu Identify renal progenitor cells, determine their role in patterning the embryonic kidney, and relate these events to kidney regeneration.
Jon Johnson, PhD
Program 1: Neuroscience (CNUP)
The Johnson lab studies the physiology, biophysics, structure, pharmacology, and regulation of glutamate receptors
Ken Jordan, PhD
Program 1: Chemistry
Program 2:
The Jordan group uses computational methods to elucidate fundamental processes in Chemistry.
Valerian Kagan, PhD, DSc
Program 2:
Karl Kandler, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Plasticity of neuronal circuits during development and in pathology, focusing on the central auditory system
Lawrence Kane, PhD
lkane@pitt.edu 1. Signal Transduction. 2.The role of the Akt kinase in NF-kB and T cell activation. 3. Role of TIM proteins in T cell activation.
Daniel Kaplan, MD, PhD
Program 2:
To understand how skin resident immune cells (e.g. dendritic cells, T cells) interact with specific pathogens.
Erin Kershaw, MD
Program 2:
The role of intracellular lipid metabolism and adipose tissue biology in normal metabolism and disease using basic and translational approaches
Saleem Khan, PhD
khan@pitt.edu Role of microRNAs in human papillomavirus-associated cancers & in aging
Samira Kiani, MD
Program 2:
Our lab is interested in using the designer DNA binding proteins such as Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and Zinc Finger proteins to develop novel gene and (epi)-gene editing tools for in vivo therapeutics.
Kang Kim, PhD
Program 1: Bioengineering
Program 2:
Develop & translate state of the art noninvasive imaging technologies to improve disease diagnosis, guide therapy, and evaluate therapeutic efficacy
Carl Kingsford, PhD
carlk@cs.cmu.edu We develop optimization algorithms for the analysis of genomic sequences andbiological networks
Thomas Kleyman, MD
kleyman@pitt.edu Cellular, structural and molecular studies of epithelial ion channels
Richard Koerber, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Development, plasticity and pain processing in sensory neurons and in the spinal dorsal horn.
David Koes , PhD
Program 2:
Predicting, modeling, and simulating potential therapeutic agents and their interactions with target molecules is a powerful new first step in the drug discovery process.
Dennis Kostka, PhD
Program 2:
Ultimately, our goal is to generate, test, and confirm hypotheses that are relevant to human health.
Sandra Kuhlman, PhD
skuhlman@cmu.edu The goal of my research program is to understand how neural networks in the cortex are altered during new skill acquisition to promote appropriate behavioral responses and to understand how the circuitry for learning is established during development.
Bernhard Kuhn, MD
bernhard.kuhn2@chp.edu Our research is on whether and to what extent mammalian hearts can regenerate themselves, and to develop regenerative therapies for heart failure.
Eric Lagasse, PharmD, PhD
lagasse@pitt.edu Our research is focused primarily on stem cell biology and cell-based therapy for a variety of diseases including cancer and organ failure.
Seema Lakdawala, PhD
Program 2:
Our lab studies the molecular properties contributing to the epidemiological success of influenza A viruses to better predict future pandemics
Fadi Lakkis, MD
Program 2:
Innate and adaptive immune response to transplanted organs and the mechanisms of transplantation tolerance.
Philip LeDuc, PhD
prl@andrew.cmu.edu Linking mechanics to biochemistry through exploring the science of molecular to cellular biomechanics through nano- & micro-technology & comp biology
Adrian Lee, PhD
Program 2: Human Genetics
Molecular profiling (genomic, transcriptomic, proteomic) of women’s cancers, mouse modeling, and predictive biomarkers for targeted therapy
Janet Lee, MD
Program 2:
Host susceptibility to lung injury and the factors that promote persistence of inflammation
Robin Lee, PhD
robinlee@pitt.edu Our research combines principles of systems, synthetic and computational biology with engineering to understand how information flows through inflammatory signaling pathways in tumor and immune cells.
David Lewis, MD
Program 1: Neuroscience (CNUP)
Functional architecture of the prefrontal cortex and schizophrenia.
Philana Lin, MD, MSC
Program 2:
Our lab is focused on the host protective immune responses to M. tuberculosis, a major factor in outcome of infection.
Steven Little, PhD
Program 1: Bioengineering
Program 2:
Drug Delivery, Biomimetics, Immunotherapeutics, Tissue Engineering, Biomaterials, Synthetic Systems
Cecilia Lo, PhD
el36@pitt.edu Our research objectives are focused on elucidating the genetic causes and developmental mechanisms of human congenital heart disease (CHD).
Binfeng Lu, PhD
Program 2:
Discovery of novel molecular and cellular pathways regulating key steps of T cell-mediated immune responses in antitumor immunity and autoimmunity
Xinghua Lu, MD, PhD, MS
Program 2:
computational methods facilitating personalized precision medicine for cancers
Peter Lucas, MD, PhD
Program 2:
The relationship between chronic inflammation and the development of vascular, metabolic, and neoplastic diseases
Beatriz Luna, PhD
Program 1: Neuroscience (CNUP)
Brain basis of cognitive maturation through adolescence to adulthood.
Aman Mahajan MD PhD
Program 1: Bioengineering
Program 2:
Neural network control of cardiac arrhythmias and myocardial function; Neuromodulation for treating sudden cardiac death; Studying perioperative healthcare delivery; Role of perioperative interventions in altering clinical outcomes and mortality
Wendy Mars, PhD
Program 2:
Understanding how cytokines and proteases controlling normal liver growth become deviant, leading to the development of cirrhosis and liver cancer
Bruce McClane, PhD
Program 2:
human and animal pathogen Clostridium perfringens
Colleen McClung, PhD
Program 1: Neuroscience (CNUP)
Program 2:
We are interested in the molecular mechanisms of psychiatric disorders with a particular focus on the role of the circadian clock in these disorders
Stephen Meriney, PhD
Program 1: Neuroscience (CNUP)
Dr. Meriney's research program focuses on mechanisms of synaptic plasticity in the neuromuscular system in both normal and disease conditions.
Diana Metes, MD
Program 2:
Human immunology: Innate and adaptive immune responses to latent viruses and to allo-antigens after organ transplantation
Natasa Miskov-Zivanov, PhD
Program 2:
The integration of powerful technologies and system strategies is transforming medical research and clinical practice at an unprecedented rate.
Aaron Mitchell, PhD
Program 2:
Our studies focus on Candida albicans, a leading fungal pathogen that can cause both mucosal and invasive infections.
Tom Mitchell, PhD
Program 2:
We focus on research and education in all areas of statistical machine learning
Pamela Moalli, MD, PhD
Program 1: Bioengineering
Program 2:
Pelvic Floor Disorders, Prolapse Meshes
Satdarshan Monga, MD
Program 2:
Aimed at elucidating the cellular and molecular mechanisms of liver pathophysiology
Patrick Moore, MD
psm9@pitt.edu The study of human tumor viruses
Ana Mora, MD
Program 2:
Penelope Morel, MD
Program 2:
Autoimmunity & the control of T cell immune responses; Systems biology approaches to immune response to infectious organisms
Michael Morowitz, MD
Program 1: Human Genetics
Program 2:
Pathogenicity of Intestinal Microbes in Milk Fed and Formula Fed Premature Infants - See more at: http://www.chp.edu/find-a-doctor/service-providers/michael-morowitz-143687#sthash.jOu6Y9fO.dpuf
Alison Morris, MD, MS
Program 2:
HIV-associated lung disease; HIV-associated emphysema; Role of Pneumocystis in COPD
Matthew Neal, MD
Program 2:
Kari Nejak-Bowen, MBA, PhD
Program 2:
To understand the cellular and molecular basis of liver injury, regeneration, and cholestatic liver disease
Anne Newman, MD, MPH
Program 1: Epidemiology
Program 2:
Cardiovascular Disease Epidemiology;Subclinical atherosclerosis: Associations with aging, disability & frailty;Sarcopenia & disability
Vishwajit Nimgaonkar, MD, PhD
Program 1: Human Genetics
Program 2:
Genetics of schizophrenia/bipolar disorder;functional genomics using induced pluripotent stem cell (iPSC) based models;gene/environment interactions
Enrico Novelli, MD, MS
Program 2:
the mechanisms of vascular dysfunction in sickle cell disease. With interest in the vascular pathology that underlies cognitive dysfunction. Also novel imaging biomarkers and diagnostic imaging strategies in sickle cell disease.
Steffi Oesterreich, PhD
oesterreichs@upmc.edu Hormone response and treatment resistance in breast and ovarian cancer, including the analysis of aberrant genetic and epigenetic changes
Patricia Opresko, PhD
Program 2:
Trevor Orchard, MBBCh, MMedSci
Program 1: Epidemiology
Program 2:
The epidemiology of diabetes complications and cardiovascular disease.
Kyle Orwig, PhD
keo6@pitt.edu Spermatogonial stem cells (SSCs) and male germ lineage development
Tim Oury, MD, PhD
Program 2:
Oxidative mechanisms of pulmonary fibrosis, acute lung injury, inflammation, and pneumonia. The laboratory also studies the role of RAGE in the lung
John Pacella, MD, MS
Program 1: Bioengineeering
Program 2:
Developing strategies to improve myocardial microvascular perfusion. Involving in vitro and in vivo models, and spans multiple disciplines: acoustic physics, polymer chemistry, physiology, cardiology, vascular biology, and advanced cardiac imaging.
Quasar Padiath, MBBS, PhD
Program 1: Human Genetics
Program 2:
molecular mechanisms underlying various neurological disorders using human genetic approaches as well as research on animal and cell culture models
Patrick Pagano, PhD
Program 2:
NADPH oxidase (Nox) & reactive oxygen species in signaling, vascular dysfunction and cardiopulmonary disease; Nox drug therapy development
Michael Palladino, PhD
Program 1: Neuroscience (CNUP)
We use Drosophila, mice and human cell lines to elucidate pathogenesis and develop new therapies for mitochondria and neurodegenerative diseases.
Udai Pandey, PhD
Program 1: Neuroscience (CNUP)
Program 2: Human Genetics
Human neurodegenerative diseases, motor neuron degeneration and traumatic brain injury
Ashok Panigrahy, MD
Program 2:
Andreas Pfenning, PhD
Program 2:
What features do the genes and the genomes of vocal learning species have in common relative to those without the ability?
Mary Phillips, MD
phillipsml@upmc.edu Identification of neural correlates that underlie the symptoms of specific abnormalities in emotion processing in people with mood disorders
Todd Przybycien, PhD
Program 2:
Applied biophysics: protein structural, adsorption and aggregation behavior during bioprocessing and delivery. Biosensing: pressure ulcer detection.
James Roberts, MD
Program 1: Epidemiology
Our current work addresses preeclampsia and it pathophysiology in high and low resource se
Mark Roberts, MD, MPP
Program 2:
He is interested in the use of observational data analysis for causal inference, as well as in the measurement and inclusion of patient preferences into treatment decisions and the use of electronic health records for research.
Caterina Rosano, MD, MPH
Program 1: Epidemiology
Program 2:
Brain adaptation, neuroepidemiological approaches to the causes, biomarkers and consequences of brain aging, advanced data reduction analyses
Sarah Ross, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Understanding the functional organization of spinal microcircuits using molecular genetic, electrophysiological, optogenetic & behavioral approaches
Maria Rubio, MD, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Research focuses on investigating neuron-glia communication in the normal hearing and in the hearing impaired
Warren Ruder, PhD, MS
Program 1: Bioengineering
Program 2:
Our mission includes both understanding the fundamental biology of natural bioprocessing systems as well as re-engineering these systems with synthetic control circuits.
Lindsay Sabik, PhD
Program 2:
Dr. Sabik is a health economist & health services researcher focused on investigating the role of state & federal policies in affecting healthcare access, utilization, & health outcomes among low-income populations, with a particular focus on cancer care.
Ulka Sachdev, MD
Srivatsun Sadagopan, PhD
Program 1: Neuroscience (CNUP)
Program 2: Bioengineering
Neural mechanisms underlying complex sound perception in health and disease.
Yoel Sadovsky, MD
ysadovsky@mwri.magee.edu Our lab focuses on molecular mechanisms underlying placental development and its function in supporting fetal growth and maternal-fetal communication
Dean Salisbury, PhD
Program 1: Neuroscience
Andrew Schwartz, PhD
Program 1: Neuroscience (CNUP)
Program 2: Bioengineering
Cerebral basis for volitional movement and cortical neural prosthetics.
Russell Schwartz, PhD
russells@andrew.cmu.edu I work in the general area of computational biology, with emphasis on computational genetics and the modeling and simulation of biological systems
Melanie Scott, MD, PhD
Program 2:
Innate immune responses to sterile injury and infection with a focus on inflammasome activation and immune activation by endogenous danger signals
Rebecca Seal, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Our work is focused on neural circuits that mediate two neurological conditions: pain and Parkinson’s disease. We are also developing novel therapies to treat these conditions.
Ervin Sejdic, PhD
Program 1: Bioengineering
Advanced information systems in medicine; Anticipatory medical devices; Assistive technologies; Biomedical Signal Processing; Gait analysis
Susan Sesack, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Dr. Sesack’s research focuses on the monoamine and cortical systems that regulate cognitive and emotional behaviors.
Steven Shapiro, MD
Program 2:
Understanding the biological functions of matrix degrading proteinases in health and disease.
Mark Shlomchik, MD, PhD
Program 2:
My lab is interested in the establishment of long term B cell immunity and in pathogenesis of systemic autoimmune diseases and graft vs host disease
Jason Shoemaker, PhD
Program 2:
Our group aims to develop computational approaches to exploit large-scale data to promote disease treatment discovery and optimization.
Sanjeev Shroff, PhD
Program 1: Bioengineering
Program 2:
Cardiac structure-function: contractile/regulatory proteins, post-translational regulation, dyssynchrony
Matthew Smith, PhD
Program 1: Neuroscience (CNUP)
Program 2: Bioengineering
Neurophysiology of visual perception and cognition, computational neuroscience, cortical circuitry, neural population coding
Tom Smithgall, PhD
tsmithga@pitt.edu Non-receptor protein-tyrosine kinase structure, regulation and signal transduction in cancer, AIDS, and embryonic stem cell biology
Alexander Sorkin, PhD
Program 2: Neuroscience (CNUP)
Mechanisms and functional role of endocytic trafficking of EGF receptor in cancer cells and the dopamine transporter in the brain
Gwendolyn Sowa, MD, PhD
Program 1: Bioengineering
Program 2:
Biomarker discovery, beneficial effects of mechanical loading, & implementation in targeted exercise therapies for musculoskeletal conditions
Richard Steinman, MD, PhD
steinman@pitt.edu Mechanisms of white blood cell differentiation & its inhibition in leukemias; Mechanisms of stem cell differentiation & growth control
Sean Stocker, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Autonomic dysfunction in cardiovascular disease and body fluid homeostasis
Donna Stolz, PhD
Program 2:
Angiogenesis and vascularization events in liver regeneration and remodeling
Walter Storkus, PhD
Program 2: Bioengineering
The immunobiology and immunotherapy of melanoma and renal cell carcinoma
Adam Straub, PhD
Program 2:
The Straub laboratory investigates redox cell signaling mechanisms that control endothelial and smooth muscle biology in the microcirculation.
Peter Strick, PhD
Program 1: Neuroscience (CNUP)
1) the control of voluntary movement by the cerebral cortex, 2) the functional organization of the basal ganglia and cerebellum, and 3) unraveling the circuitry of the central nervous system.
Arohan Subramanya, MD
ars129@pitt.edu We study cell signaling networks that coordinate kidney tubule salt transport, blood pressure, and potassium homeostasis
Dandan Sun, MD, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Understanding the role of ion transporter proteins (sodium-potassium-chloride cotransporter, sodium/proton exchanger, and sodium/calcium exchangers) in ionic dysregulation and neurodegeneration associated with stroke and hypoxic ischemic encephalopathy.
Alan Sved, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Central neural control of the autonomic nervous system and cardiovascular function; neurobiology of nicotine pharmacology.
Robert Sweet, MD
Program 1: Neuroscience (CNUP)
Program 2:
Loss and altered plasticity of auditory cortex synapses in schizophrenia; mediators of vulnerability to psychosis in Alzheimer disease.
Galen Switzer, PhD
Program 2:
Psychosocial issues in organ and tissue donation and transplantation.
Pei Tang, PhD
ptang@pitt.edu Understanding the molecular mechanism(s) of action of general anesthetics.
Michael Tarr, PhD
Program 1: Neuroscience (CNUP)
Program 2: Psychology (CMU)
Human visual object, face and scene processing using behavioral psychophysics, graphics, neuroimaging (fMRI, MEG, DSI), and computational modeling.
Bradley Taylor, PhD
Program 1: Neuroscience (CNUP)
Program 2:
Neurobiology and Pharmacology of Chronic Pain and Analgesia
Amantha Thathiah, PhD
Program 1: Neuroscience (CNUP)
We use molecular, biochemical, and cellular approaches to study the pathogenesis of Alzheimer’s disease.
Angus Thomson, PhD, DSc
Program 2:
Regulation of the immune response; role of dendritic cells and T cells in tolerance induction; mechanism of action of novel immune suppressants
Rebecca Thurston, PhD
Program 2: Epidemiology
Women’s health, cardiovascular disease in women, brain aging in women, menopause, midlife aging, trauma
Dennis Trumble, PhD
Program 2:
Computational cardiac mechanics; cardiac assist devices; muscle-powered implants; medical device design and optimization; tissue-device interfaces; the neural basis of cognition; science education
Michael Tsang, PhD
Program 2:
Zebrafish Heart Development and Regeneration
George Tseng, ScD
Program 1: Human Genetics
Program 2:
Interests in statistical and computational methods to combine information from multiple high-throughput omics data sets
Robert Turner, PhD
Program 1: Neuroscience (CNUP)
Basal ganglia-cortical dysfunction in Parkinson's disease and therapeutic mechanisms of deep brain stimulation
Heth Turnquist, PhD
Program 2:
Understanding and controlling the cytokine networks that direct immune responses responsible for both protective and pathological immunity.
Thanos Tzounopoulos, PhD
Program 2: Neuroscience (CNUP)
We study synaptic mechanisms and their role during normal and pathological sensory processing (tinnitus).
Zsolt Urban, PhD
Program 1: Human Genetics
Inherited disorders of elastic fibers, transforming growth factor-beta signaling, cellular and zebrafish models
Kenneth Urish, MD, PhD
Program 1: Bioengineering
Program 2:
The focus of the Urish laboratory is on understanding implant biofilm dynamics during an infection and identifying new treatment strategies.
Bennett Van Houten, PhD
vanhoutenb@upmc.edu 1) Repair of DNA damage in nuclear and mitochondrial genomes; 2) Structure and function of nucleotide excision repair proteins.
Dario Vignali, PhD
Program 2:
The inhibitory mechanisms, including inhibitory receptors & regulatory T cells, that limit anti-tumor immunity in cancer patients.
Flordeliza Villanueva, MD
villanuevafs@upmc.edu The development of medical diagnostic and therapeutic strategies that are based on ultrasound and ultrasound contrast agents (microbubbles).
Shyam Visweswaran, MD, PhD
Program 2:
Computer-aided diagnosis and patient-specific prediction, genomic and precision medicine, clinical decision support, research data warehouse
Gerard Vockley, MD, PhD
Program 1: Human Genetics
Program 2:
David Vorp, PhD
Program 1: Bioengineering
Vascular bioengineering in the context of vascular tissue engineering, aortic aneurysm, and regenerative medicine”
William Wagner, PhD
Program 1: Bioengineering
Program 2:
Cardiovascular engineering with projects that address medical device biocompatibility and design, tissue engineering, and imaging.
David Waldeck, PhD
Program 1: Chemistry
Program 2:
Fundamental understanding of electron transfer reactions, electron transport in supramolecular structures, and nanophotonics
Yu-Li Wang, PhD
Program 2:
Mechanisms of cell division and migration; mechanics of cell-matrix interactions; mechanotransduction
Stephen Weber, PhD
Program 1: Chemistry
Program 2:
Bioanalysis, capillary separations, sampling from tissues and single cells.
Kurt Weiss, MD
weiskr@upmc.edu Dr. Weiss directs a basic science laboratory dedicated to the study of sarcomas--cancerous tumors that arise in the musculoskeletal tissues.
Ora Weisz, PhD
weisz@pitt.edu Regulation of protein traffic in polarized epithelial cells.
Alan Wells, MD
wellsa@upmc.edu Integrative biology of wound healing and tumor metastasis, from molecules and cells through tissues and animals to humans
Sally Wenzel, MD
Program 2:
Focuses on asthma phenotypes and the molecular mechanisms, particularly in the airway epithelium that control them
Clayton Wiley, MD, PhD
Program 2: Neuroscience (CNUP)
Pathogenesis of Neuroinflammation, Neurodegeneration and Neurovirology
John Williams, MD
Program 2:
the cell entry, immunity, and pathogenesis of human metapneumovirus (HMPV).
Xiangqun (Sean) Xie, MD, PhD
Program 2:
disease domain-specific system chemogenomics knowledgebase and personalized medicine
Eric Xing, PhD, PhD
Program 2:
development of machine learning and statistical methodology, & large-scalecomputational system and architecture, for solving problems within systems
Jianhua Xing, PhD
Program 2:
My lab currently focuses on Epithelial-to-Mesenchymal Transiton (EMT). EMT is defined as the conversion of epithelial cells to mesenchymal cells, characterized by loss of cell-cell adhesion and increased cell motility.
Yan Xu, PhD
Program 2: Neuroscience (CNUP)
Designed receptors as therapeutic targets for pain; mechanisms of low-affinity drug action; mapping of unconscious brain;stem cell therapy for stroke
Byron Yu, PhD
byronyu@cmu.edu Neural signal processing; machine learning approaches in neuroscience; neural prosthetic systems
Jian Yu, PhD
Program 2:
To understand the roles and regulation of cell death in normal & cancerous tissues, & mechanism-based development of cell death-targeted therapeutics
Jian-Min Yuan, MD, PhD
Program 1: Epidemiology
Program 2:
Environmental exposure and gene-environmental interaction in the etiology of cancer Biomarkers for cancer risk assessment and early detection Chemopreventive effect of dietary agents for primary prevention of cancer
Lin Zhang, PhD
Program 2:
Genetic basis of differential sensitivity to anticancer drugs; genetic alterations that cause drug resistance; mechanisms of drug-induced apoptosis