Skip to main content

Aaron Sun MD, PhD

  • Resident, Johns Hopkins Hospital, Baltimore, MD

    Education & Training

  • University of Pittsburgh, MD, 2021
  • University of Pittsburgh, PhD, 2018
  • Rutgers University, BS, 2013
Representative Publications

Sun AX, Lin H, Fritch MR, Shen H, Alexander PG, DeHart M, Tuan RS. Chondrogenesis of human bone marrow mesenchymal stem cells in 3-dimensional, photocrosslinked hydrogel constructs: Effect of cell seeding density and material stiffness. Acta Biomater. 2017 Aug;58:302-311. doi: 10.1016/j.actbio.2017.06.016. Epub 2017 Jun 10. PMID: 28611002; PMCID: PMC5813286.

Whitehead A, Zhang Y, McCabe Dunn J, Sherer EC, Lam YH, Stelmach J, Sun A, Shiroda M, Orr RK, Waddell ST, Raghavan S. 2017. Selective Formation of Functionalized α-Quaternary Malononitriles toward 5,5-Disubstituted Pyrrolopyrimidinones. Organic Letters. 4448-4451. PMID: 28812897.

Sun AX, Numpaisal P, Gottardi R, Shen H, Yang G, Tuan RS. 2016. Cell and Biomimetic Scaffold-Based Approaches for Cartilage Regeneration. Operative Techniques in orthopaedics. 135-146. PMID:

Londono R, Sun AX, Tuan RS, Lozito TP. TISSUE REPAIR AND EPIMORPHIC REGENERATION: AN OVERVIEW. Curr Pathobiol Rep. 2018 Mar;6(1):61-69. doi: 10.1007/s40139-018-0161-2. Epub 2018 Feb 4. PMID: 29967714; PMCID: PMC6025457.

Deng Y, Sun AX, Overholt KJ, Yu GZ, Fritch MR, Alexander PG, Shen H, Tuan RS, Lin H. Enhancing chondrogenesis and mechanical strength retention in physiologically relevant hydrogels with incorporation of hyaluronic acid and direct loading of TGF-β. Acta Biomater. 2019 Jan 1;83:167-176. doi: 10.1016/j.actbio.2018.11.022. Epub 2018 Nov 17. PMID: 30458242; PMCID: PMC6733255.

Shen H , Lin H , Sun AX, Song S , Zhang Z , Dai J , Tuan RS . Chondroinductive factor-free chondrogenic differentiation of human mesenchymal stem cells in graphene oxide-incorporated hydrogels. J Mater Chem B. 2018 Feb 14;6(6):908-917. doi: 10.1039/c7tb02172k. Epub 2018 Jan 23.

Sun AX, Londono R, Hudnall ML, Tuan RS, Lozito TP. Differences in neural stem cell identity and differentiation capacity drive divergent regenerative outcomes in lizards and salamanders. Proc Natl Acad Sci U S A. 2018 Aug 28;115(35):E8256-E8265. doi: 10.1073/pnas.1803780115. Epub 2018 Aug 13. PMID: 30104374; PMCID: PMC6126763.

Sun AX, Prest TA, Fowler JR, Brick RM, Gloss KM, Li X, DeHart M, Shen H, Yang G, Brown BN, Alexander PG, Tuan RS. Conduits harnessing spatially controlled cell-secreted neurotrophic factors improve peripheral nerve regeneration. Biomaterials. 2019 May;203:86-95. doi: 10.1016/j.biomaterials.2019.01.038. Epub 2019 Feb 19.

Brick RM, Sun AX, Tuan RS. Neurotrophically Induced Mesenchymal Progenitor Cells Derived from Induced Pluripotent Stem Cells Enhance Neuritogenesis via Neurotrophin and Cytokine Production. Stem Cells Transl Med. 2018 Jan;7(1):45-58. doi: 10.1002/sctm.17-0108. Epub 2017 Dec 7. PMID: 29215199; PMCID: PMC5746147.

Sun AX, Lin H, Fritch MR, Shen H, Alexander PG, DeHart M, Tuan RS. Chondrogenesis of human bone marrow mesenchymal stem cells in 3-dimensional, photocrosslinked hydrogel constructs: Effect of cell seeding density and material stiffness. Acta Biomater. 2017 Aug;58:302-311. doi: 10.1016/j.actbio.2017.06.016. Epub 2017 Jun 10.

Shen H, Lin H, Sun AX, Song S, Wang B, Yang Y, Dai J, Tuan RS. Acceleration of chondrogenic differentiation of human mesenchymal stem cells by sustained growth factor release in 3D graphene oxide incorporated hydrogels. Acta Biomater. 2020 Mar 15;105:44-55. doi: 10.1016/j.actbio.2020.01.048. Epub 2020 Feb 5.

Sun AX, Lin H, Beck AM, Kilroy EJ, Tuan RS. Projection Stereolithographic Fabrication of Human Adipose Stem Cell-Incorporated Biodegradable Scaffolds for Cartilage Tissue Engineering. Front Bioeng Biotechnol. 2015 Aug 18;3:115. doi: 10.3389/fbioe.2015.00115. PMID: 26347860; PMCID: PMC4539543.

Career Advisor
Aaron Batista, PhD
Thesis Advisor
Rocky Tuan, PhD
Program
Bioengineering
Dissertation Title

ASSISTED NERVE REGENERATION UTILIZING NOVEL NERVE CONDUITS WITH WALL-ENCAPSULATED CELLS

Trainee
Past
Graduate Year
2021
Training Start Year
2013