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Alexander Chang

    Education & Training

  • Johns Hopkins University, BA, 2020
Representative Publications

Pandey SP, Bender MJ, McPherson AC, Phelps CM, Sanchez LM, Rana M, Hedden L, Sangani KA, Chen L, Shapira JH, Siller M, Goel C, VerdĂș EF, Jabri B, Chang A, Chandran UR, Mullett SJ, Wendell SG, Singhi AD, Tilstra JS, Pierre JF, Arteel GE, Hinterleitner R, Meisel M. Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis. Cell Host Microbe. 2022 Jul 13;30(7):1003-1019.e10. doi: 10.1016/j.chom.2022.05.006. Epub 2022 Jun 2. PMID: 35658976; PMCID: PMC9841318.

Lyu B, Xu Y, Inker LA, Chang AR, Nolin TD, Coresh J, Grams ME, Shin JI. Discordance in GFR Estimating Equations and Dosing Guidance by Body Mass Index and Age. Am J Kidney Dis. 2023 Oct;82(4):505-507. doi: 10.1053/j.ajkd.2023.01.453. Epub 2023 Apr 7. PMID: 37030585; PMCID: PMC11228967.

Williams BA, Rajpura J, Paprocki YM, Kumar N, Voyce S, Brady JP, Chang A. Temporal trends in cardiovascular outcomes and costs among patients with type 2 diabetes. Am Heart J. 2023 Nov;265:161-169. doi: 10.1016/j.ahj.2023.07.012. Epub 2023 Jul 27. PMID: 37516264.

Wang N, He Y, Liu S, Makarcyzk MJ, Lei G, Chang A, Alexander PG, Hao T, Padget AM, de Pedro N, Menelaos T, Lin H. Engineering osteoarthritic cartilage model through differentiating senescent human mesenchymal stem cells for testing disease-modifying drugs. Sci China Life Sci. 2022 Feb;65(2):309-327. doi: 10.1007/s11427-021-1933-7. Epub 2021 Jun 4. PMID: 34109475; PMCID: PMC10077511.

Louis K, Bailly E, Macedo C, Lau L, Ramaswami B, Chang A, Chandran U, Landsittel D, Gu X, Chalasani G, Zeevi A, Randhawa P, Singh H, Lefaucheur C, Metes D. T-bet+CD27+CD21- B cells poised for plasma cell differentiation during antibody-mediated rejection of kidney transplants. JCI Insight. 2021 Jun 22;6(12):e148881. doi: 10.1172/jci.insight.148881. PMID: 34032636; PMCID: PMC8262465.

Banerjee H, Nieves-Rosado H, Kulkarni A, Murter B, McGrath KV, Chandran UR, Chang A, Szymczak-Workman AL, Vujanovic L, Delgoffe GM, Ferris RL, Kane LP. Expression of Tim-3 drives phenotypic and functional changes in Treg cells in secondary lymphoid organs and the tumor microenvironment. Cell Rep. 2021 Sep 14;36(11):109699. doi: 10.1016/j.celrep.2021.109699. PMID: 34525351; PMCID: PMC8482289.

Williams BA, Voyce S, Blankenship JC, Chang AR. Association between the diagnostic classification of newly diagnosed coronary artery disease and future heart failure development. Coron Artery Dis. 2023 Aug 1;34(5):341-350. doi: 10.1097/MCA.0000000000001243. Epub 2023 May 1. PMID: 37139564.

Schoedel K, Miller V, Osei-Hwedieh D, Watters R, Duensing A, John I, Chandran U, Chang A, Soman V, Weiss K. Differential expression of angiogenesis markers HSP70, HSP90, VEGF and pERK1/2 in both components of dedifferentiated chondrosarcomas. J Bone Oncol. 2021 May 18;29:100370. doi: 10.1016/j.jbo.2021.100370. PMID: 34094840; PMCID: PMC8167291.

Schoedel K, Heim T, Duensing A, Lohse I, Presutti L, Belayneh R, Bhogal S, Singh-Varma A, Chang A, Chandran U, Marker D, Szabo-Rogers H, Weiss K. Grade 2, 3 and Dedifferentiated Chondrosarcomas: A Comparative Study of Isocitrate Dehydrogenase-Mutant and Wild-Type Tumors with Implications for Prognosis and Therapy. Cancers (Basel). 2024 Jan 5;16(2):247. doi: 10.3390/cancers16020247. PMID: 38254737; PMCID: PMC10813891.

Student Year
G2
Career Advisor
James Faeder, PhD
Program
Computational Biology
Trainee
Current
Training Start Year
2021