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Ananya Mukundan PhD

    Education & Training

  • University of Michigan, BS, 2016
Representative Publications

van Dinther M, Cunningham KT, Singh SP, White MPJ, Campion T, Ciancia C, van Veelen PA, de Ru AH, González-Prieto R, Mukundan A, Byeon CH, Staggers SR, Hinck CS, Hinck AP, Dijke PT, Maizels RM. CD44 acts as a coreceptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-β mimic. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2302370120. doi: 10.1073/pnas.2302370120. Epub 2023 Aug 17. PMID: 37590410; PMCID: PMC10450677.

Singh SP, Smyth DJ, Cunningham K, Mukundan A, Byeon CH, Hinck CS, White MPJ, Ciancia C, Wosowska N, Sanders A, Jin R, Lilla S, Zanivan S, Schoenherr C, Inman G, van Dinther M, Ten Dijke P, Hinck AP, Maizels RM. The helminth TGF-β mimic TGM4 is a modular ligand that binds CD44, CD49d and TGF-β receptors to preferentially target myeloid cells. bioRxiv [Preprint]. 2023 Nov 15:2023.11.13.566701. doi: 10.1101/2023.11.13.566701. PMID: 38014296; PMCID: PMC10680678.

Mukundan A, Byeon CH, Hinck CS, Cunningham K, Campion T, Smyth DJ, Maizels RM, Hinck AP. Convergent evolution of a parasite-encoded complement control protein-scaffold to mimic binding of mammalian TGF-β to its receptors, TβRI and TβRII. J Biol Chem. 2022 Jun;298(6):101994. doi: 10.1016/j.jbc.2022.101994. Epub 2022 Apr 29. PMID: 35500648; PMCID: PMC9163516.

McManus CM, Bouchery T, Suleiman M, Kildemoes AO, Ferguson A, Wang T, Finlay CM, Chan R, Renahan T, Mukundan A, Nkurunungi G, Bobardt SD. Hydra 2022: return of the interactive conference on helminth parasitology after the pandemic. Trends Parasitol. 2022 Dec;38(12):999-1007. doi: 10.1016/j.pt.2022.09.013. Epub 2022 Nov 2. PMID: 36335007.
Student Year
MS4
Career Advisor
Angela Gronenborn, PhD
Thesis Advisor
Andrew Hinck, PhD
Program
Molecular Biophysics and Structural Biology
Trainee
Current
Training Start Year
2016