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Andrew Lamade MD, PhD

  • Resident, Cleveland Clinic Foundation, Cleveland, OH

    Education & Training

  • University of Pittsburgh, MD, 2022
  • University of Pittsburgh, PhD, 2020
  • The College of Wooster, BA, 2013
Representative Publications

Anthonymuthu TS, Kenny EM, Lamade AM, Gidwani H, Krehel NM, Misse A, Gao X, Amoscato AA, Straub AC, Kagan VE, Dezfulian C, Bayir H. Lipidomics Detection of Brain Cardiolipins in Plasma Is Associated With Outcome After Cardiac Arrest. Crit Care Med. 2019;47(4):e292-e300. Epub 2019/03/12. doi: 10.1097/CCM.0000000000003636. PubMed PMID: 30855329; PMCID: PMC6622168.

Anthonymuthu TS, Kenny EM, Lamade AM, Kagan VE, Bayir H. Oxidized phospholipid signaling in traumatic brain injury. Free Radic Biol Med. 2018;124:493-503. Epub 2018/07/03. doi: 10.1016/j.freeradbiomed.2018.06.031. PubMed PMID: 29964171; PMCID: PMC6098726.

Bayir H, Anthonymuthu TS, Tyurina YY, Patel SJ, Amoscato AA, Lamade AM, Yang Q, Vladimirov GK, Philpott CC, Kagan VE. Achieving Life through Death: Redox Biology of Lipid Peroxidation in Ferroptosis. Cell Chem Biol. 2020;27(4):387-408. Epub 2020/04/11. doi: 10.1016/j.chembiol.2020.03.014. PubMed PMID: 32275865; PMCID: PMC7218794.

Dezfulian C, Kenny E, Lamade A, Misse A, Krehel N, St Croix C, Kelley EE, Jackson TC, Uray T, Rackley J, Kochanek PM, Clark RS, Bayir H. Mechanistic characterization of nitrite-mediated neuroprotection after experimental cardiac arrest. J Neurochem. 2016;139(3):419-31. Epub 2016/10/25. doi: 10.1111/jnc.13764. PubMed PMID: 27507435; PMCID: PMC5247267.

Krainz T, Lamade AM, Du L, Maskrey TS, Calderon MJ, Watkins SC, Epperly MW, Greenberger JS, Bayir H, Wipf P, Clark RSB. Synthesis and Evaluation of a Mitochondria-Targeting Poly(ADP-ribose) Polymerase-1 Inhibitor. ACS Chem Biol. 2018;13(10):2868-79. Epub 2018/09/06. doi: 10.1021/acschembio.8b00423. PubMed PMID: 30184433; PMCID: PMC6402482.

Lamade AM, Anthonymuthu TS, Hier ZE, Gao Y, Kagan VE, Bayir H. Mitochondrial damage & lipid signaling in traumatic brain injury. Exp Neurol. 2020;329:113307. Epub 2020/04/15. doi: 10.1016/j.expneurol.2020.113307. PubMed PMID: 32289317; PMCID: PMC7237325.

Lamade AM, Kenny EM, Anthonymuthu TS, Soysal E, Clark RSB, Kagan VE, Bayir H. Aiming for the target: Mitochondrial drug delivery in traumatic brain injury. Neuropharmacology. 2019;145(Pt B):209-19. Epub 2018/07/17. doi: 10.1016/j.neuropharm.2018.07.014. PubMed PMID: 30009835; PMCID: PMC6309489.

Career Advisor
Donald DeFranco, PhD
Thesis Advisor
Hulya Bayir, MD
Program
Molecular Pharmacology
Dissertation Title

Role of Regulated Necrotic Cell Death in Acute Injury: Ferroptosis, Necroptosis, Parthanatos.

Trainee
Past
Graduate Year
2022
Training Start Year
2013