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Brandon Lehrich

    Education & Training

  • University of California – Irvine, BS, 2018
Representative Publications

Lehrich BM, Delgado ER, Yasaka TM, Liu S, Cao C, Liu Y, Taheri M, Guan X, Koeppen H, Singh S, Liu JJ, Singh-Varma A, Krutsenko Y, Poddar M, Hitchens TK, Foley LM, Liang B, Rialdi A, Rai RP, Patel P, Riley M, Bell A, Raeman R, Dadali T, Luke JJ, Guccione E, Ebrahimkhani MR, Lujambio A, Chen X, Maier M, Wang Y, Broom W, Tao J, Monga SP. Precision targeting of β-catenin induces tumor reprogramming and immunity in hepatocellular cancers. Res Sq [Preprint]. 2024 Dec 12:rs.3.rs-5494074. doi: 10.21203/rs.3.rs-5494074/v1. PMID: 39711542; PMCID: PMC11661417.

Lehrich BM, Tao J, Liu S, Hirsch TZ, Yasaka TM, Cao C, Delgado ER, Guan X, Lu S, Pan L, Liu Y, Singh S, Poddar M, Bell A, Singhi AD, Zucman-Rossi J, Wang Y, Monga SP. Development of mutated β-catenin gene signature to identify CTNNB1 mutations from whole and spatial transcriptomic data in patients with HCC. JHEP Rep. 2024 Aug 20;6(12):101186. doi: 10.1016/j.jhepr.2024.101186. PMID: 39583094; PMCID: PMC11582745.

Lehrich BM, Delgado ER. Lipid Nanovesicle Platforms for Hepatocellular Carcinoma Precision Medicine Therapeutics: Progress and Perspectives. Organogenesis. 2024 Dec 31;20(1):2313696. doi: 10.1080/15476278.2024.2313696. Epub 2024 Feb 15. PMID: 38357804; PMCID: PMC10878025.

Zhao L, Qiu Z, Yang Z, Xu L, Pearce TM, Wu Q, Yang K, Li F, Saulnier O, Fei F, Yu H, Gimple RC, Varadharajan V, Liu J, Hendrikse LD, Fong V, Wang W, Zhang J, Lv D, Lee D, Lehrich BM, Jin C, Ouyang L, Dixit D, Wu H, Wang X, Sloan AE, Wang X, Huan T, Mark Brown J, Goldman SA, Taylor MD, Zhou S, Rich JN. Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism. Nat Cancer. 2024 Jan;5(1):147-166. doi: 10.1038/s43018-023-00658-0. Epub 2024 Jan 3. PMID: 38172338.

Lehrich BM, Zhang J, Monga SP, Dhanasekaran R. Battle of the biopsies: Role of tissue and liquid biopsy in hepatocellular carcinoma. J Hepatol. 2024 Mar;80(3):515-530. doi: 10.1016/j.jhep.2023.11.030. Epub 2023 Dec 15. PMID: 38104635; PMCID: PMC10923008.

Lehrich BM, Monga SP. Learning human liver biology in humanized mice. Cell Res. 2024 Jan;34(1):9-10. doi: 10.1038/s41422-023-00877-1. PMID: 37730939; PMCID: PMC10770126.

Lehrich BM, Abiri A, Nguyen TV, Bitner BF, Tong CCL, Kuan EC. Mutational landscape and predictors of survival in head and neck mucosal melanoma. Int Forum Allergy Rhinol. 2024 Apr;14(4):858-861. doi: 10.1002/alr.23267. Epub 2023 Sep 7. PMID: 37676479; PMCID: PMC10918024.

Student Year
G3
Career Advisor
Marie DeFrances, MD, PhD
Thesis Advisor
Pal Monga, MD
Program
Cellular and Molecular Pathology
Trainee
Current
Training Start Year
2020