- University of Pittsburgh, PhD, 2025
- Wesleyan University, BA, 2016
Education & Training
Pirooz Zareie, Eric S Weiss, Daniel H Kaplan, Laura K Mackay, Cutaneous T cell immunity, Nat Immunol, 2025 May 7. doi: 10.1038/s41590-025-02145-3. Online ahead of print.
Eric S Weiss, Toshiro Hirai, Haiyue Li, Andrew Liu, Shannon Baker, Ian Magill, Jacob Gillis, Youran R. Zhang, Torben Ramcke, Kazuo Kurihara, The ImmGen Consortium OpenSource T cell Project, David Masopust 7, Niroshana Anandasabapathy, Harinder Singh, David Zemmour, Laura K. Mackay, Daniel H. Kaplan, Epidermal Resident Memory T Cell Fitness Requires Antigen Encounter in the Skin, eLife, accepted April 2025
Liu AW, Zhang YR, Chen CS, Edwards TN, Ozyaman S, Ramcke T, McKendrick LM, Weiss ES, Gillis JE, Laughlin CR, Randhawa SK, Phelps CM, Kurihara K, Kang HM, Nguyen SN, Kim J, Sheahan TD, Ross SE, Meisel M, Sumpter TL, Kaplan DH. Scratching promotes allergic inflammation and host defense via neurogenic mast cell activation. Science. 2025 Jan 31;387(6733):eadn9390. doi: 10.1126/science.adn9390. Epub 2025 Jan 31. PMID: 39883751.
Tissue resident CD8 memory T cells (TRM) are a recently appreciated, highly abundant, non-circulating, long-lived subset of memory T cells that play an important role in protecting against re-infections. However, the signals required for their formation and differentiation remain largely unknown. Using acute inflammatory models, tumor models, as well as transcriptional analysis, I explored the molecular signals that modulate TRM differentiation and function.