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Hector Nieves-Rosado PhD

    Education & Training

  • University of Pittsburgh, Ph.D, 2023
  • University of Puerto Rico-Mayaguez Campus, BS, 2016
Representative Publications

Banerjee, H., Nieves-Rosado, HM, Kulkarni, A., Murter, B., McGrath, K. V., Chandran, U. R., . . . Kane, LP. Expression of Tim-3 drives phenotypic and functional changes in Treg cells in secondary lymphoid organs and the tumor microenvironment. Cell Rep; 2021. (PMID 34525351).

Nieves-Rosado HM., Jacobs JL., Naqvi A., Mellors JW., Macatangay BJC., Kane LP. TIM-3 signaling contributes to the suppressive capacity of Tregs from people with HIV on antiretroviral therapy. J Leukoc Biol; 2023. (PMID: 37350502).

Nieves-Rosado, HM., Banerjee, H., Gocher-Demske, A., Manandhar, P., Mehta, I., Ezenwa, O., Xie, B., Murter, B., Das, J., Vignali, DAA., Delgoffe, GM., Kane, LP. Tim-3 is required for Treg-mediated promotion of T cell exhaustion and viral persistence during chronic LCMV infection. Journal of Immunology; 2024.

Peralta, RM., Xie, B., Lontos, K., Nieves-Rosado, HM., Spahr, K., Ford, RB., Quann, K., Frisch, A., Dean, V., Philbin, M., Cillo, AR., Gingras, S., Poholek, AC., Kane, LP., Rivadeneira, DB., Delgoffe GM. Dysfunction of exhausted T cells is enforced by MCT11-mediated lactate metabolism. Nat. Immunol; 2024.

 

Student Year
MS4
Career Advisor
JoAnne Flynn, PhD
Thesis Advisor
Lawrence Kane, PhD
Program
Microbiology and Immunology
Dissertation Title

Tim-3+ Treg control viral persistence and effector T cell responses

Trainee
Current
Training Start Year
2018