- Vassar College, B.A., 2011
- University of Pittsburgh, PhD, 2023
Education & Training
Gale J, Aizenman E. The physiological and pathophysiological roles of copper in the nervous system. Eur J Neurosci. 2024 Jul;60(1):3505-3543. doi: 10.1111/ejn.16370. Epub 2024 May 15. PMID: 38747014.
Gale, J. R., Hartnett-Scott, K., Ross, M. M., Rosenberg, P. A., & Aizenman, E. (2023). Copper induces neuron-sparing, ferredoxin 1-independent astrocyte toxicity mediated by oxidative stress. Journal of neurochemistry, 10.1111/jnc.15961. Advance online publication. https://doi.org/10.1111/jnc.15961
Hernandez-Espinosa, D. R., Gale, J. R., Scrabis, M. G., & Aizenman, E. (2023). Microglial reprogramming by Hv1 antagonism protects neurons from inflammatory and glutamate toxicity. Journal of neurochemistry, 165(1), 29–54. https://doi.org/10.1111/jnc.15760
Krall, R., Gale, J. R., Ross, M. M., Tzounopoulos, T., & Aizenman, E. (2022). Intracellular zinc signaling influences NMDA receptor function by enhancing the interaction of ZnT1 with GluN2A. Neuroscience letters, 790, 136896. https://doi.org/10.1016/j.neulet.2022.136896
Gleixner, A. M., Verdone, B. M., Otte, C. G., Anderson, E. N., Ramesh, N., Shapiro, O. R., Gale, J. R., Mauna, J. C., Mann, J. R., Copley, K. E., Daley, E. L., Ortega, J. A., Cicardi, M. E., Kiskinis, E., Kofler, J., Pandey, U. B., Trotti, D., & Donnelly, C. J. (2022). NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility. Nature communications, 13(1), 3380. https://doi.org/10.1038/s41467-022-31098-6
Gale, J. R., Gedeon, J. Y., Donnelly, C. J., & Gold, M. S. (2022). Local translation in primary afferents and its contribution to pain. Pain, 163(12), 2302–2314. https://doi.org/10.1097/j.pain.0000000000002658
Gale, J. R., Kosobucki, G. J., Hartnett-Scott, K. A., & Aizenman, E. (2021). Imprecision in Precision Medicine: Differential Response of a Disease-Linked GluN2A Mutant to NMDA Channel Blockers. Frontiers in pharmacology, 12, 773455. https://doi.org/10.3389/fphar.2021.773455
Liu, H. Y., Gale, J. R., Reynolds, I. J., Weiss, J. H., & Aizenman, E. (2021). The Multifaceted Roles of Zinc in Neuronal Mitochondrial Dysfunction. Biomedicines, 9(5), 489. https://doi.org/10.3390/biomedicines9050489
Insights into the mechanism of copper-ionophore mediated toxicity in glial cells.