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Jorna Sojati PhD

    Education & Training

  • University of Pittsburgh, PhD, 2024
  • Villanova University, MS, 2018
Representative Publications

Espinoza-Candelaria GJ, Albert J, Sojati J, Martin JM, Michaels MG, Green M. Varicella-Zoster Virus Pretransplant Vaccination and Posttransplant Infections Among Pediatric Solid Organ Recipients in the Two-Dose Varicella Era: A Single-Center, Multi-Organ Retrospective Study. Pediatr Transplant. 2024 Aug;28(5):e14822. doi: 10.1111/petr.14822. PMID: 39054880.

Eddens T, Lue J, Sojati J, Tomani M, Dede O, Kernan K, Kietz D, Larkin A, Chong H, Coffey K. A novel splice-site mutation in NFKB1 presenting as common variable immunodeficiency and postoperative hyperinflammation responsive to anti-IL-1 therapy. J Allergy Clin Immunol Pract. 2024 Oct;12(10):2873-2876.e1. doi: 10.1016/j.jaip.2024.06.024. Epub 2024 Jun 18. PMID: 38901617; PMCID: PMC11464186.

Eddens T, Parks OB, Lou D, Fan L, Sojati J, Ramsey MJ, Schmitt L, Salgado CM, Reyes-Mugica M, Evans A, Zou HM, Oury TD, Byersdorfer C, Chen K, Williams JV. Monocyte Production of C1q Potentiates CD8+ T-Cell Function Following Respiratory Viral Infection. Am J Respir Cell Mol Biol. 2024 Sep;71(3):294-306. doi: 10.1165/rcmb.2024-0004OC. PMID: 38696270; PMCID: PMC11376238.

Zhang Y, Xu J, Miranda-Katz M, Sojati J, Tollefson SJ, Manni ML, Alcorn JF, Sarkar SN, Williams JV. Distinct roles for type I and type III interferons in virulent human metapneumovirus pathogenesis. PLoS Pathog. 2024 Feb 5;20(2):e1011840. doi: 10.1371/journal.ppat.1011840. PMID: 38315735; PMCID: PMC10868789.

Sojati J, Murali A, Rapsinski G, Williams JV. Do Not Throw Away Your Shot: Pilot Study in Improving Medical School Curricula Through Focused Vaccine Education. AJPM Focus. 2023 Dec 23;3(2):100178. doi: 10.1016/j.focus.2023.100178. PMID: 38312525; PMCID: PMC10835123.

Sojati J, Zhang Y, Williams JV. Clinical human metapneumovirus isolates show distinct pathogenesis and inflammatory profiles but similar CD8+ T cell impairment. mSphere. 2024 Jan 30;9(1):e0057023. doi: 10.1128/msphere.00570-23. Epub 2024 Jan 10. PMID: 38197640; PMCID: PMC10826344.

Sojati J, Murali A, Pressimone C, Dakroub A. A Cross-Sectional Factor Analysis of COVID-19 and Influenza Vaccination Decisions in a Racially Diverse Western Pennsylvania Community. J Prim Care Community Health. 2023 Jan-Dec;14:21501319231212287. doi: 10.1177/21501319231212287. PMID: 37994782; PMCID: PMC10668581.

Murali A, Sojati J, Levochkina M, Pressimone C, Griffith K, Fan E, Dakroub A. A Cross-Sectional Analysis of Community Perceptions of Flu and COVID-19 Vaccines at Turtle Creek Primary Care Center. Community Health Equity Res Policy. 2024 Jul;44(4):439-451. doi: 10.1177/2752535X231205665. Epub 2023 Oct 14. PMID: 37837451.

Parks OB, Eddens T, Sojati J, Lan J, Zhang Y, Oury TD, Ramsey M, Erickson JJ, Byersdorfer CA, Williams JV. Terminally exhausted CD8+ T cells contribute to age-dependent severity of respiratory virus infection. Immun Ageing. 2023 Aug 1;20(1):40. doi: 10.1186/s12979-023-00365-5. PMID: 37528458; PMCID: PMC10391960.

Ortega-Gonzalez P, Taylor G, Jangra RK, Tenorio R, Fernandez de Castro I, Mainou BA, Orchard RC, Wilen CB, Brigleb PH, Sojati J, Chandran K, Sachse M, Risco C, Dermody TS. Reovirus infection is regulated by NPC1 and endosomal cholesterol homeostasis. PLoS Pathog. 2022 Mar 9;18(3):e1010322. doi: 10.1371/journal.ppat.1010322. PMID: 35263388; PMCID: PMC8906592.

Student Year
MS3
Career Advisor
JoAnne Flynn, PhD
Thesis Advisor
John Williams, MD
Program
Microbiology and Immunology
Dissertation Title

Type III Interferon-Mediated Responses in Upper and Lower Respiratory Tracts During Infection with Human Metapneumovirus Clinical Isolates

Trainee
Current
Training Start Year
2018