- University of Pittsburgh, PhD, 2024
- University of Pittsburgh, BS, 2018
Education & Training
Parks OB, Williams JV. Method to Assess Immunosenescent CD8+ T Cells in Respiratory Viral Infections. Methods Mol Biol. 2025;2857:33-43. doi: 10.1007/978-1-0716-4128-6_4. PMID: 39348053.
Antos D, Parks OB, Duray AM, Abraham N, Michel JJ, Kupul S, Westcott R, Alcorn JF. Cell-intrinsic regulation of phagocyte function by interferon lambda during pulmonary viral, bacterial super-infection. PLoS Pathog. 2024 Aug 23;20(8):e1012498. doi: 10.1371/journal.ppat.1012498. PMID: 39178311; PMCID: PMC11376568.
Eddens T, Parks OB, Lou D, Fan L, Sojati J, Ramsey MJ, Schmitt L, Salgado CM, Reyes-Mugica M, Evans A, Zou HM, Oury TD, Byersdorfer C, Chen K, Williams JV. Monocyte Production of C1q Potentiates CD8+ T-Cell Function Following Respiratory Viral Infection. Am J Respir Cell Mol Biol. 2024 Sep;71(3):294-306. doi: 10.1165/rcmb.2024-0004OC. PMID: 38696270; PMCID: PMC11376238.
Sojati J, Parks OB, Zhang Y, Walters S, Lan J, Eddens T, Lou D, Fan L, Chen K, Oury TD, Williams JV. IFN-λ drives distinct lung immune landscape changes and antiviral responses in human metapneumovirus infection. mBio. 2024 May 8;15(5):e0055024. doi: 10.1128/mbio.00550-24. Epub 2024 Mar 26. PMID: 38530032; PMCID: PMC11077986.
Eddens T, Parks OB, Zhang Y, Manni ML, Casanova JL, Ogishi M, Williams JV. PD-1 signaling in neonates restrains CD8+ T cell function and protects against respiratory viral immunopathology. Mucosal Immunol. 2024 Jun;17(3):476-490. doi: 10.1016/j.mucimm.2023.12.004. Epub 2024 Jan 3. PMID: 38176655; PMCID: PMC11180597.
Parks OB, Antos D, Eddens T, Walters S, Johnson M, Oury TD, Gottschalk RA, Erickson JJ, Williams JV. PD-1 Impairs CD8+ T Cell Granzyme B Production in Aged Mice during Acute Viral Respiratory Infection. Immunohorizons. 2023 Nov 1;7(11):771-787. doi: 10.4049/immunohorizons.2300094. PMID: 38015461; PMCID: PMC10696419.
Parks OB, Eddens T, Sojati J, Lan J, Zhang Y, Oury TD, Ramsey M, Erickson JJ, Byersdorfer CA, Williams JV. Terminally exhausted CD8+ T cells contribute to age-dependent severity of respiratory virus infection. Immun Ageing. 2023 Aug 1;20(1):40. doi: 10.1186/s12979-023-00365-5. PMID: 37528458; PMCID: PMC10391960.
Freeman KG, Robotham AC, Parks OB, Abad L, Jacobs-Sera D, Lauer MJ, Podgorski JM, Zhang Y, Williams JV, White SJ, Kelly JF, Hatfull GF, Pope WH. Virion glycosylation influences mycobacteriophage immune recognition. Cell Host Microbe. 2023 Jul 12;31(7):1216-1231.e6. doi: 10.1016/j.chom.2023.05.028. Epub 2023 Jun 16. PMID: 37329881; PMCID: PMC10527164.
Parks OB, Eddens T, Zhang Y, Oury TD, McElroy A, Williams JV. Human Metapneumovirus Reinfection in Aged Mice Recapitulates Increased Disease Severity in Elderly Humans Infected with Human Metapneumovirus. Immunohorizons. 2023 Jun 1;7(6):398-411. doi: 10.4049/immunohorizons.2300026. PMID: 37261717; PMCID: PMC10321313.
Parks OB, Keith M, Squires JH, Venkat VL, Mahmood B. Liver Microabscesses in a Premature Neonate With Eosinophilic Colitis. ACG Case Rep J. 2022 Jul 1;9(7):e00817. doi: 10.14309/crj.0000000000000817. PMID: 35784499; PMCID: PMC9246066.
The role of age and complement in CD8+ T cell function during human metapneumovirus (HMPV) infection