Philip Mannes PhD | Medical Scientist Training Program

Education & Training

University of Pittsburgh, Ph.D, 2023

Dartmouth College, BA, 2016

Representative Publications

Mannes PZ, Adams TS, Farsijani S, Barnes CE, Latoche JD, Day KE, Nedrow JR, Ahangari F, Kaminski N, Lee JS, Tavakoli S. Noninvasive assessment of the lung inflammation-fibrosis axis by targeted imaging of CMKLR1. Sci Adv. 2024 Jun 21;10(25):eadm9817. doi: 10.1126/sciadv.adm9817. Epub 2024 Jun 19. PMID: 38896611; PMCID: PMC11186491.

Zhu Q, Barnes CE, Mannes PZ, Latoche JD, Day KE, Nedrow JR, Novelli EM, Anderson CJ, Tavakoli S. Targeted imaging of very late antigen-4 for noninvasive assessment of lung inflammation-fibrosis axis. EJNMMI Res. 2023 Jun 5;13(1):55. doi: 10.1186/s13550-023-01006-0. PMID: 37273103; PMCID: PMC10240482.

Mannes PZ, Barnes CE, Latoche JD, Day KE, Nedrow JR, Lee JS, Tavakoli S. 2-deoxy-2-[¹⁸F]fluoro-D-glucose Positron Emission Tomography to Monitor Lung Inflammation and Therapeutic Response to Dexamethasone in a Murine Model of Acute Lung Injury. Mol Imaging Biol. 2023 Aug;25(4):681-691. doi: 10.1007/s11307-023-01813-w. Epub 2023 Mar 20. PMID: 36941514; PMCID: PMC10027262.

Mannes PZ, Barnes CE, Biermann J, Latoche JD, Day KE, Zhu Q, Tabary M, Xiong Z, Nedrow JR, Izar B, Anderson CJ, Villanueva FS, Lee JS, Tavakoli S. Molecular imaging of chemokine-like receptor 1 (CMKLR1) in experimental acute lung injury. Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2216458120. doi: 10.1073/pnas.2216458120. Epub 2023 Jan 10. PMID: 36626557; PMCID: PMC9934297.

Mannes PZ, Tavakoli S. Imaging Immunometabolism in Atherosclerosis. J Nucl Med. 2021 Jul 1;62(7):896-902. doi: 10.2967/jnumed.120.245407. Epub 2021 May 7. PMID: 33963045; PMCID: PMC8882876.

Mannes PZ, Wang TL, Ma W, Selzer J, Blanco C. Student Substance Use Policies in US Allopathic Medical Schools: A National Study. JAMA Psychiatry. 2021 Dec 1;78(12):1393-1395. doi: 10.1001/jamapsychiatry.2021.2666. PMID: 34586347; PMCID: PMC8482301.

Demirdelen S, Mannes PZ, Aral AM, Haddad J, Leers SA, Gomez D, Tavakoli S. Divergence of acetate uptake in proinflammatory and inflammation-resolving macrophages: implications for imaging atherosclerosis. J Nucl Cardiol. 2021. Epub 2021/01/10. doi: 10.1007/s12350-020-02479-5. PubMed PMID: 33420659.

Wagner S , Sudhamalla B , Mannes P, Sappa S , Kavoosi S , Dey D , Wang S , Islam K . Engineering bromodomains with a photoactive amino acid by engaging 'Privileged' tRNA synthetases. Chem Commun (Camb). 2020 Mar 28;56(25):3641-3644. doi: 10.1039/c9cc09891g. Epub 2020 Feb 28. PMID: 32107512; PMCID: PMC7146825.

Student Year

MS4

Career Advisor

Pal Monga, MD

Thesis Advisor

Sina Tavakoli, MD, PhD

Program

Cellular and Molecular Pathology

Dissertation Title

Molecular imaging of chemokine-like receptor 1 (CMKLR1) for non-invasive monitoring of monocyte-derived macrophages in experimental lung injury and remodeling.

Trainee

Current

Training Start Year

2017