Faculty
Dr. Sabik is a health economist & health services researcher focused on investigating the role of state & federal policies in affecting healthcare access, utilization, & health outcomes among low-income populations, with a particular focus on cancer care.
We develop materials-based, engineering strategies to control the self-organization and assembly of various cell types into tissues using nanoscale fabrication and 3D bioprinting. Understanding of higher-order function in biological systems.
Dr. Sachdev-Ost's research examines how the nuclear protein HMGB1 is released from ischemic muscle, finding that its absence hinders recovery and that inflammasomes and platelets may affect its local availability.
Neural mechanisms underlying complex sound perception in health and disease.
Our lab focuses on molecular mechanisms underlying placental development and its function in supporting fetal growth and maternal-fetal communication
We use interdisciplinary approaches to understand how the nervous system regulates homeostasis and disease, including pain syndromes, cancer, and immune responses.
I work in the general area of computational biology, with emphasis on computational genetics and the modeling and simulation of biological systems
Our work is focused on neural circuits that mediate two neurological conditions: pain and Parkinson’s disease. We are also developing novel therapies to treat these conditions.
My lab is interested in the establishment of long term B cell immunity and in pathogenesis of systemic autoimmune diseases and graft vs host disease
Neurophysiology of visual perception and cognition, computational neuroscience, cortical circuitry, neural population coding
Non-receptor protein-tyrosine kinase structure, regulation and signal transduction in cancer, AIDS, and embryonic stem cell biology
Biomarker discovery, beneficial effects of mechanical loading, & implementation in targeted exercise therapies for musculoskeletal conditions
We have pioneered research in a historically understudied area of ophthalmology, the ocular microbiome and its effect(s) on ocular disease. Normally a highly contentious topic in ophthalmology, the ocular microbiome does, indeed, tune local immunity to prevent fungal and bacterial infection.
Mechanisms of white blood cell differentiation & its inhibition in leukemias; Mechanisms of stem cell differentiation & growth control
Our studies will be a direct outgrowth of this work, where we will focus on the molecular, cellular, and in vivo contribution of somatic hemoglobins and CytB5Rs as it pertains to vascular physiology and disease.
Our work is focused on the relationship between biomolecular condensates, cytoplasmic crowding, cell fluid volume and size control, and kidney tubule function in health and disease
Loss and altered plasticity of auditory cortex synapses in schizophrenia; mediators of vulnerability to psychosis in Alzheimer disease.
Psychosocial issues in organ and tissue donation and transplantation.