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Publications

Trainee: Past
Faculty Member: Dennis Trumble, PhD
Publications:

E. Aranda-Michel et al., "Miniaturized Robotic End-Effector With Piezoelectric Actuation and Fiber Optic Sensing for Minimally Invasive Cardiac Procedures," in IEEE Sensors Journal, vol. 18, no. 12, pp. 4961-4968, 15 June15, 2018, doi: 10.1109/JSEN.2018.2828940.

Aranda-Michel E, Waldman LK, Trumble DR. Left ventricular simulation of cardiac compression: Hemodynamics and regional mechanics. PLoS One. 2019 Oct 31;14(10):e0224475. doi: 10.1371/journal.pone.0224475. PMID: 31671155; PMCID: PMC6822737.

Han J, Kubala M, Aranda-Michel E, Trumble DR. Ventricle-specific epicardial pressures as a means to optimize direct cardiac compression for circulatory support: A pilot study. PLoS One. 2019 Jul 5;14(7):e0219162. doi: 10.1371/journal.pone.0219162. PMID: 31276569; PMCID: PMC6611657.

Aranda-Michel E, Bianco V, Kilic A, Gleason TG, Navid F, Sultan I. Mortality and Readmissions After On-Pump Versus Off-Pump Redo Coronary Artery Bypass Surgery. Cardiovasc Revasc Med. 2020 Jul;21(7):821-825. doi: 10.1016/j.carrev.2019.12.008. Epub 2019 Dec 5. PMID: 31836478.

Bianco, V, Aranda‐Michel, E, Sultan, I, et al. Inconsistent correlation between procedural volume and publicly reported outcomes in adult cardiac operations. J Card Surg. 2019; 34: 1194‐ 1203. https://doi.org/10.1111/jocs.14218

Aranda-Michel E, Yousef S, Sultan I, Kilic A. Septic coronary embolism in a deceptive case of presumed isolated tricuspid valve endocarditis. J Card Surg. 2019 Oct;34(10):1130-1132. doi: 10.1111/jocs.14198. Epub 2019 Aug 2. PMID: 31374581.

Aranda-Michel E, Bianco V, Sultan I, Gleason TG, Navid F, Kilic A. Predictors of increased costs following index adult cardiac operations: Insights from a statewide publicly reported registry. J Card Surg. 2019 Aug;34(8):708-713. doi: 10.1111/jocs.14117. Epub 2019 Jul 3. PMID: 31269297.

Aranda-Michel E, Bianco V, Kilic A, Gleason TG, Sultan I. Endovascular management of spontaneous rupture of the left subclavian artery. J Card Surg. 2019 Jul;34(7):645-646. doi: 10.1111/jocs.14091. Epub 2019 Jun 18. PMID: 31212383.

Aranda-Michel E, Kilic A, Gleason TG, Bianco V, Sultan I. Diagnostic dilemma in prosthetic valve endocarditis: Computed tomography to the rescue. J Card Surg. 2019 Apr;34(4):208-210. doi: 10.1111/jocs.14001. Epub 2019 Feb 25. PMID: 30803027.

Aranda-Michel E, Kilic A, Bianco V, Gleason TG, Sultan I. Aortitis Masquerading as Intramural Hematoma of the Ascending Aorta. Ann Thorac Surg. 2019 May;107(5):e353. doi: 10.1016/j.athoracsur.2018.12.049. Epub 2019 Jan 28. PMID: 30703366.

Han J, Aranda-Michel E, Trumble DR. Muscle-Powered Counterpulsation for Untethered, Non-Blood-Contacting Cardiac Support: A Path to Destination Therapy. IEEE Trans Biomed Eng. 2020 Nov;67(11):3035-3047. doi: 10.1109/TBME.2020.2974826. Epub 2020 Feb 18. PMID: 32086191; PMCID: PMC7587079.

Daniel Shiwarski*, Joshua Tashman*, Alkiviadis Tsamis, Jacqueline Bliley, Malachi Blundon, Edgar Aranda-Michel, Quentin Jallerat, John Szymanski, Brooke McCartney, and Adam Feinberg. Fibronectin-Based Nanomechanical Biosensors to Map 3D Surface Strains in Live Cells and Tissues. Nature Communications. Oct 2020.

Edgar Aranda-Michel, Valentino Bianco, Keith Dufendach, Arman Kilic, Andreas Habertheuer, Rishab Humar, Forozan Navid,Yisi Wang, and Ibrahim Sultan. Mid-term outcomes of subcoronary stentless porcine valve versus stented aortic valve replacement. Journal of Cardiac Surgery. 2020

Seese L, Aranda-Michel E, Sultan I, Morell VO, Mathier MA, Mulukutla SR, Saba S, Dueweke EJ, Levenson JE, Kilic A. Programmatic Responses to the Coronavirus Pandemic: A Survey of 502 Cardiac Surgeons. Ann Thorac Surg. 2020 Sep;110(3):761-763. doi: 10.1016/j.athoracsur.2020.04.014. Epub 2020 Apr 28. PMID: 32360389; PMCID: PMC7187822.

Aranda-Michel E, Bianco V, Kilic A, Gleason TG, Sultan I. Acute type A aortic dissection with complete intimal intussusception into the descending aorta. J Card Surg. 2020 Jul;35(7):1626-1627. doi: 10.1111/jocs.14599. Epub 2020 May 3. PMID: 32362006.

L. Seese, E. Aranda-Michel, L. Huckaby, M. Keebler, G. Hickey, M. Mathier, I. Sultan, T. Gleason, A. Kilic. Development and Validation of a Risk Score to Predict One-Year Mortality after Bridge to Heart Transplantation with Contemporary Durable Left Ventricular Assist Devices. The Journal of Heart and Lung Transplantation. 2020.

Trainee Name: Wesley Brown MD, PhD
Trainee: Past
Faculty Member: Alex Deiters, PhD
Publications:

Cell Lineage Tracing in Zebrafish Embryos with an Expanded Genetic Code Brown, W.; Liu, J.; Tsang, M.; Deiters, A. ChemBioChem 2018, 19, 1244-1249. Highlighted as a Very Important Paper by ChemBioChem.

Light-Activation of Cre Recombinase in Zebrafish Embryos through Genetic Code Expansion, Brown, W.; Deiters, A. Methods Enzym. 2019, 624, 265-281.

Zhou W, Brown W, Bardhan A, Delaney M, Ilk AS, Rauen RR, Kahn SI, Tsang M, Deiters A. Spatiotemporal Control of CRISPR/Cas9 Function in Cells and Zebrafish using Light-Activated Guide RNA. Angew Chem Int Ed Engl. 2020 Jun 2;59(23):8998-9003. doi: 10.1002/anie.201914575. Epub 2020 Apr 6. PMID: 32160370; PMCID: PMC7250724.

Brown W, Liu J, Deiters A. Genetic Code Expansion in Animals. ACS Chem Biol. 2018;13(9):2375-86. Epub 2018/08/21. doi: 10.1021/acschembio.8b00520. PubMed PMID: 30125487; PMCID: PMC7026698.

Brown W, Zhou W, Deiters A. Regulating CRISPR/Cas9 Function through Conditional Guide RNA Control. Chembiochem. 2021;22(1):63-72. Epub 2020/08/25. doi: 10.1002/cbic.202000423. PubMed PMID: 32833316.

Zhou, W., Brown, W., Bardhan, A., Tsang, M., & Deiters, A. (2021). Optical Control of Base Editing and Transcription through Light‐Activated Guide RNA. ChemPhotoChem, 5(11), 984-988.

Brown, W., Bardhan, A., Darrah, K., Tsang, M., & Deiters, A. (2022). Optical Control of MicroRNA Function in Zebrafish Embryos. Journal of the American Chemical Society, 144(37), 16819-16826.

Brown, W., Albright, S., Tsang, M., & Deiters, A. (2022). Optogenetic Protein Cleavage in Zebrafish Embryos. ChemBioChem, e202200297.

Brown, W., Galpin, J. D., Rosenblum, C., Tsang, M., Ahern, C. A., & Deiters, A. (2023). Chemically Acylated tRNAs are Functional in Zebrafish Embryos. Journal of the American Chemical Society.

Brown, W., Wesalo, J., Tsang, M., & Deiters, A. (2023). Engineering small molecule switches of protein function in zebrafish embryos. Journal of the American Chemical Society, 145(4), 2395-2403.

Brown, W., Rosenblum, C., & Deiters, A. (2023). Small-Molecule Phosphine Activation of Protein Function in Zebrafish Embryos with an Expanded Genetic Code. In Genetically Incorporated Non-Canonical Amino Acids: Methods and Protocols (pp. 247-263). New York, NY: Springer US.

Brown, W., Wesalo, J., Samanta, S., Luo, J., Caldwell, S. E., Tsang, M., & Deiters, A. (2023). Genetically Encoded Aminocoumarin Lysine for Optical Control of Protein–Nucleotide Interactions in Zebrafish Embryos. ACS Chemical Biology.

Brown W, Davidson LA, Deiters A. Expanding the Genetic Code of Xenopus laevis Embryos. ACS Chem Biol. 2024 Feb 16;19(2):516-525. doi: 10.1021/acschembio.3c00686. Epub 2024 Jan 26. PMID: 38277773; PMCID: PMC10877573.

 

Trainee Name: Ansen Burr MD, PhD
Trainee: Past
Faculty Member: Timothy Hand, Ph.D.
Publications:

Ansen H.P. Burr, Junyi Ji, Kadir Ozler, Onur Eskiocak, Brian Yueh, Ashley Menk, Ana Costa, Natalie Rittenhouse, Chris Marshall, Pailin Chiaranunt, Lauren Mullinax, Abigail Overacre-Delgoffe, Vaugh Cooper, Amanda Poholek, Greg Delgoffe, Semir Beyaz, Timothy Hand. “Dietary sugar alters colonocyte pyruvate metabolism and impairs the early proliferative response to damage.” Cell. Mol. Gastroenterol. Hepatol. May 10, 2023, DOI: https://doi.org/10.1016/j.jcmgh.2023.05.001
10.

Chelseá Johnson-Hence, Kathyayini Gopalakrishna, Kara Coffey, Ansen H.P. Burr, Syed Rahman, Yelissa Sosa, Justin Tometich, Jishnu Das, Timothy W. Hand. “Stability and heterogeneity in the anti-microbiota repertoire of human milk-derived Immunoglobulin A.” J Exp Med (2023) 220 (8): e20220839. DOI: https://doi.org/10.1084/jem.20220839

Alfonso Santos-Lopez, Melissa J Fritz, Jeffrey B Lombardo, Ansen H.P. Burr, Victoria A Heinrich, Christopher W Marshall, Vaughn S Cooper, “Evolved resistance to a novel cationic peptide antibiotic requires high mutation supply”, Evolution, Medicine, and Public Health, Volume 10, Issue 1, 2022, Pages 266–276, DOI: https://doi.org/10.1093/emph/eoac022

Overacre-Delgoffe A.E., Cillo A.R., Bumgarner H.J., Burr A.H.P., Tometich J.T., Bhattacharjee A., Bruno T.C., Vignali D.A.A. and T.W. Hand. Microbiome-specific T follicular helper cells drive tertiary lymphoid structures and anti-tumor immunity against colorectal cancer 2021. Immunity. 2021 Dec 14;54(12):2812-2824.e4. doi: 10.1016/j.immuni.2021.11.003.

Van Der Kraak L.A., Schneider C., Dang V., Burr A.H.P., Weiss E.S., Hand T.W. and S.W. Canna Genetic and commensal induction of Interleukin-18 drive intestinal epithelial MHC class II via Interferon-g. Mucosal Immunology. 2021 Jun 8.  doi: 10.1038/s41385-021-00419-1

Bhattacharjee A., Burr A.H.P., Overacre-Delgoffe A.E., Tometich J.T., Yang D., Huckestein B.R., Linehan J.L., Spencer S.P., Hall J.A., Harrison O.J., Fonseca D.M., Norton, E.B., Belkaid Y. and T.W. Hand. Environmental Enteric Dysfunction induces intestinal regulatory T cells that inhibit local CD4+ T cell responses and impair the efficacy of oral vaccines. Immunity. 2021 Aug 10;54(8):1745-1757 PMID: 34348118

Gopalakrishna KP, Macadangdang BR, Rogers MB, Tometich JT, Firek BA, Baker R, Ji J, Burr AHP, Ma C, Good M, Morowitz MJ, Hand TW. Maternal IgA protects against the development of necrotizing enterocolitis in preterm infants. Nat Med. 2019 Jul;25(7):1110-1115. doi: 10.1038/s41591-019-0480-9. Epub 2019 Jun 17. PMID: 31209335

Castillo-Dela Cruz P, Wanek AG, Kumar P, An X, Elsegeiny W, Horne W, Fitch A, Burr AHP, Gopalakrishna KP, Chen K, Methé BA, Canna SW, Hand TW, Kolls JK. Intestinal IL-17R Signaling Constrains IL-18-Driven Liver Inflammation by the Regulation of Microbiome-Derived Products. Cell Rep. 2019 Nov 19;29(8):2270-2283.e7. doi: 10.1016/j.celrep.2019.10.042. PMID: 31747600; PMCID: PMC6886715.

Burr AHP, Bhattacharjee A, Hand TW. Nutritional Modulation of the Microbiome and Immune Response. J Immunol. 2020 Sep 15;205(6):1479-1487. doi: 10.4049/jimmunol.2000419. PMID: 32900885; PMCID: PMC7490768

Trainee Name: Alison Butler MD, PhD
Trainee: Past
Faculty Member: Gretchen Chapman, PhD
Publications:

Butler A, Chapman GB. Don't Throw Your Heart Away: Increased Transparency of Donor Utilization Practices in Transplant Center Report Cards Alters How Center Performance Is Evaluated. Med Decis Making. 2022 Apr;42(3):341-351. doi: 10.1177/0272989X211038941. Epub 2021 Oct 4. PMID: 34605713.

Godown J, Butler A, Lebovitz DJ, Chapman G. Predictors of Deceased Organ Donation in the Pediatric Population. Pediatrics. 2021 Jun;147(6):e2020009506. doi: 10.1542/peds.2020-009506. Epub 2021 May 7. PMID: 33963074;.

Butler A, Chapman G, Johnson JN, Amodeo A, Böhmer J, Camino M, Davies RR, Dipchand AI, Godown J, Miera O, Pérez-Blanco A, Rosenthal DN, Zangwill S, Kirk R. Behavioral economics-A framework for donor organ decision-making in pediatric heart transplantation. Pediatr Transplant. 2020 May;24(3):e13655. doi: 10.1111/petr.13655. Epub 2020 Jan 27. PMID: 31985140.

Godown J, Schumacher KR, Butler A, Chapman G, Dipchand AI, Kaslow WW, Bearl DW, Kirk R. Patients and their family members prioritize post-transplant survival over waitlist survival when considering donor hearts for transplantation. Pediatr Transplant. 2020;24(2):e13589. Epub 2019/09/29. doi: 10.1111/petr.13589. PubMed PMID: 31562687    

Godown J, Schumacher KR, Butler A, Chapman G, Dipchand AI, Kaslow WW, Bearl DW, Kirk R. Patients and their family members prioritize post-transplant survival over waitlist survival when considering donor hearts for transplantation. Pediatr Transplant. 2020 Mar;24(2):e13589. doi: 10.1111/petr.13589. Epub 2019 Sep 27. PMID: 31562687.

Kirk R, Dipchand AI, Davies RR, Miera O, Chapman G, Conway J, Denfield S, Gossett JG, Johnson J, McCulloch M, Schweiger M, Zimpfer D, Ablonczy L, Adachi I, Albert D, Alexander P, Amdani S, Amodeo A, Azeka E, Ballweg J, Beasley G, Böhmer J, Butler A, Camino M, Castro J, Chen S, Chrisant M, Christen U, Danziger-Isakov L, Das B, Everitt M, Feingold B, Fenton M, Garcia-Guereta L, Godown J, Gupta D, Irving C, Joong A, Kemna M, Khulbey SK, Kindel S, Knecht K, Lal AK, Lin K, Lord K, Möller T, Nandi D, Niesse O, Peng DM, Pérez-Blanco A, Punnoose A, Reinhardt Z, Rosenthal D, Scales A, Scheel J, Shih R, Smith J, Smits J, Thul J, Weintraub R, Zangwill S, Zuckerman WA. ISHLT consensus statement on donor organ acceptability and management in pediatric heart transplantation. J Heart Lung Transplant. 2020 Apr;39(4):331-341. doi: 10.1016/j.healun.2020.01.1345. Epub 2020 Jan 31. PMID: 32088108.

Trainee: Past
Faculty Member: Ross, Sarah
Publications:

Patel A, Abou-Al-Shaar H, Chiang MC, Algattas HN, McDowell MM, Stone JG, Mitchell EB, Emery SP, Greene S. Neuro-Ophthalmologic Manifestations of Congenital Aqueductal Stenosis. Journal of Neurosurgery Pediatrics, Submitted October 2020.

McDowell MM*, Chiang MC*, Abou-Al-Shaar H, Zenonos GA, Wang EW, Snyderman CH, Gardner PA. Applications of endoscopic endonasal surgery in early childhood. Journal of Neurosurgery Pediatrics, Submitted, September 2020.

Chiang MC, Canto-Bustos M, Nguyen EK, Papale AE, Oswald, AMM, Ross SE. Divergent pathways emanating from the lateral parabrachial nucleus mediate separable aspects of the pain response. Neuron. 2020 Apr 8. pii: S0896-6273(20)30221-X.  doi: 10.1016/j.neuron.2020.03.014. PMID: 32289251

Chiang MC*, McDowell MM*, Weaver K, Broniscer A, Greene S. Is Schimmelpenning syndrome associated with intracranial tumors? A case report. Pediatric Neurosurgery. 2019 Mar 15; 1-6. doi: 10.1159/000497149. * These two authors contributed equally to this manuscript. PMID: 30879010

McDowell MM*, Chiang MC*, Agarwal N, Ismail N, Friedlander RM, Wecht DA. Exclusive use of fixed pressure valves for cerebrospinal fluid diversion in a modern adult cohort. Heliyon. 2018 Dec 29;4(12):e01099. doi: 10.1016/j.heliyon.2018.e01099. * These two authors contributed equally to this manuscript. PMID: 30627679

Snyder LM, Chiang MC, Loeza-Alcocer E, Omori Y, Hachisuka J, Sheahan T, Adelman PC, Sypek EI, Fulton SA, Friedman RL, Wright MC, Duque MG, Lee YS, Hu Z, Huang H, Cai X, Gale JR, Nagarajan V, Hirai T, Meerschaert KA, Scherrer G, Kaplan DH, Porreca F, Davis BM, Gold MS, Koerber HR, Ross SE. Kappa Opioid Receptor Distribution and Function in Primary Afferents. Neuron. 2018 Sep 19;99(6):1274-1288.e6. doi: 10.1016/j.neuron.2018.08.044. PMID: 30236284

Hachisuka J, Omori Y, Chiang MC, Koerber HR, Ross SE. Wind-up in lamina I spinoparabrachial neurons: a role for reverberatory circuits. Pain. 2018 Mar 23.doi: 10.1097/j.pain.0000000000001229. PMID: 29578943

Hachisuka J, Chiang MC, Ross SE. Itch and Neuropathic Itch. Pain. 2018. Jan 2; doi: 10.1097/j.pain.0000000000001141. PMID: 29389746

Zhao Y, Sivaji S, Chiang MC, Cheng A, Haadi A, Guo Z, Reed A, Kodali R, Borowski J, Frost G, Beukema P, Wills ZP. Amyloid Beta Peptides Block New Synapse Assembly by Nogo Receptor Mediated Inhibition of T-Type Calcium Channels. Neuron. 2017. Oct 11;96(2):355-372.e6. doi: 10.1016/j.neuron.2017.09.041. PMID: 29024660.

Trainee: Past
Faculty Member: Behrmann, Marlene
Publications:

Collins, E., Behrmann, M. (2020). Exemplar Learning Reveals the Representational Origins of Expert Visual Perception. Proceedings of the National Academy of Sciences. 117(20), 11167-11177. DOI: https://doi.org/10.1073/pnas.1912734117. PMID: 32366664 PMCID: PMC7245133

Collins, E., Freud, E., Kainerstorfer, J.M., Cao, J., Behrmann, M. (2019). Temporal Dynamics of Shape Processing Differentiate Contributions of Dorsal and Ventral Visual Pathways. Journal of Cognitive Neuroscience, 31(6), 821-836. DOI: https://doi.org/10.1162/jocn_a_01391 

Collins, E., Robinson, A., Behrmann, M. (2018). Distinct Neural Processes for the Perception of Familiar Versus Unfamiliar Faces Along the Visual Hierarchy Revealed by EEG. NeuroImage, 181, 120-131. DOI: 10.1016/j.neuroimage.2018.06.080. PMCID: PMC6139062

Collins, E., Dundas, E., Gabay, Y., Plaut, D.C., Behrmann, M. (2017). Hemispheric Organization in Disorders of Development. Visual Cognition, 25(4-6): 416-429. DOI:10.1080/13506285.2017.1370430 PMCID: PMC6241318

Collins, E., Park, J., Behrmann, M. (2017). Numerosity Representation is Encoded in the Human Subcortex. Proceedings of the National Academy of Sciences, 114(14), E2806–E2815. DOI: 10.1073/pnas.1613982114. PMCID: PMC5389276

Trainee Name: Raphael Crum MD, PhD
Trainee: Past
Faculty Member: Stephen Badylak, MD, PhD
Publications:

Crum RJ, Huckestien BR, Dwyer G, Mathews L, Nascari DG, Hussey GS, Turnquist HR, Alcorn JF, Badylak SF. Mitigation of influenza-mediated inflammation by immunomodulatory matrix-bound nanovesicles. Sci Adv. 2023 May 19;9(20):eadf9016. doi: 10.1126/sciadv.adf9016. Epub 2023 May 19. PMID: 37205761; PMCID: PMC10198633.

Crum RJ, Johnson SA, Jian P, et. Al. Transcriptomic, Proteomic, and Morphologic Characterization of Healing in Volumetric Muscle Loss. Tissue Engineering Part A. Accepted July 2022.

Crum RJ, Capella-Monsonis H, Badylak SF, Hussey G. Extracellular Vesicles for Regenerative Medicine Applications. Submitted to Applied Sciences. July 25, 2022.

Crum RJ, Hall K, Pineda C, Hussey G, Graham E, Li H, Badylak SF. Immunomodulatory matrix-bound nanovesicles mitigate acute and chronic pristane-induced rheumatoid arthritis. npj Regenerative Medicine. February 2, 2022.

Crum RJ, Kay J, et. Al. Bone vs All Soft Tissue Quadriceps Tendon Autografts for Anterior Cruciate Ligament Reconstruction: A Systematic Review. Arthroscopy. October 21, 2020.

Crum RJ, Hussey G, Saldin L, Dziki J, Badylak SF. Development of a colloidal, extracellular matrix hydrogel for the operative management of simple and complex anorectal fistulas. Gastroenterology. May 2020.

Hussey G, (…6…) Crum RJ, (…), Badylak SF. Ultrasonic Cavitation to prepare ECM hydrogels. Acta Biomaterialia. March 2020.

Do Amaral MCF, Frisbie J, Crum RJ, Goldstein DL, Krane CM. Hepatic transcriptome of the freeze-tolerant Cope’s gray treefrog, Dryophytes chrysoscelis: responses to cold acclimation and freezing. BMC Genomics. March 2020.

de SA D, Crum RJ, Rabuck S, et. Al. The REVision using Imaging to guide Staging and Evaluation (REVISE) in ACL Reconstruction Classification. Journal of Knee Surgery. (Accepted Aug 12, 2019)

Zhang K, Crum RJ, Samuelsson K, Cadet E, Ayeni OR, de SA D. In-office needle arthroscopy: A systematic review of indications and clinical utility. Arthroscopy. Aug 12, 2019.

Crum RJ, de SA D, Su FL, Lesniak BP, Lin A. Decreased complication profile and improved clinical outcomes of primary reverse total shoulder arthroplasty after 2010: A systematic review. Shoulder and Elbow. June 2019.

Crum RJ, de SA D, Kanakamedala A, Obioha O, Lesniak BP, Musahl V. Aperture and suspensory fixation equally efficacious for quadriceps tendon graft fixation in primary ACL reconstruction: A systematic review. Journal of Knee Surgery. April 2019.

De SA D, Arakgi M, Lian J, Crum RJ, Lin A, Lesniak BP. Labral repair versus biceps tenodesis for primary isolated type II SLAP tears: A systematic review. Arthroscopy. March 2019.

Crum RJ, de SA D, Ayeni OR, et al. No difference between extraction drilling and serial dilation for tibial tunnel preparation in anterior cruciate ligament reconstruction: a systematic review. Journal of ISAKOS: Joint Disorders & Orthopaedic Sports Medicine. 20 February 2018. 

Trainee: Past
Faculty Member: Stephen Chan, MD, PhD
Publications:

Culley MK, Chan SY. Human Endogenous Retrovirus K and Pulmonary Arterial Hypertension: A New Take on a Retro Idea. Circulation. 136,1936-38 (2017).

Culley MK, and Chan SY. Mitochondrial metabolism in pulmonary hypertension: beyond mountains there are mountains. J Clin Invest. 2018;128(9):3704-15. PMCID: PMC6118596

Cai J, Culley MK, Zhao Y, and Zhao J. The role of ubiquitination and deubiquitination in the regulation of cell junctions. Protein Cell.2018;9(9):754-69.PMCID: PMC6107491

Yu Q, Tai YY, Tang Y, Zhao J, Negi V, Culley MK, et al. BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension. Circulation. 2019;139(19):2238-55. PMCID: PMC6519484

Yu Q, Tai YY, Tang Y, Zhao J, Negi V, Culley MK, et al. BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension. Circulation.2019;139(19):2238-55.PMCID: PMC6519484

Culley MK, Perk D, and Chan SY. NFU1, Iron-Sulfur Biogenesis, and Pulmonary Arterial Hypertension: A (Metabolic) Shift in our Thinking. Am J Respir Cell Mol Biol.2019. PMCID: PMC6993537

Trainee: Past
Faculty Member: Kolls, Jay
Publications:

Kumar P, Monin L, Castillo P, Elsegeiny W, Horne W, Eddens T, Vikram A, Good M, Schoenborn AA, Bibby K, Montelaro RC, Metzger DW, Gulati AS, Kolls JK. Intestinal Interleukin-17 Receptor Signaling Mediates Reciprocal Control of the Gut Microbiota and Autoimmune Inflammation. Immunity. 2016 Mar 15;44(3):659-671. doi: 10.1016/j.immuni.2016.02.007. PMID: 26982366; PMCID: PMC4794750.

Castillo P, Kolls JK. IL-10: A Paradigm for Counterregulatory Cytokines. J Immunol. 2016 Sep 1;197(5):1529-30. doi: 10.4049/jimmunol.1601192. PMID: 27543665.

Eddens T, Elsegeiny W, Garcia-Hernadez ML, Castillo P, Trevejo-Nunez G, Serody K, Campfield BT, Khader SA, Chen K, Rangel-Moreno J, Kolls JK. Pneumocystis-Driven Inducible Bronchus-Associated Lymphoid Tissue Formation Requires Th2 and Th17 Immunity. Cell Rep. 2017 Mar 28;18(13):3078-3090. doi: 10.1016/j.celrep.2017.03.016. PMID: 28355561; PMCID: PMC5411079.

Elsegeiny W, Zheng M, Eddens T, Gallo RL, Dai G, Trevejo-Nunez G, Castillo P, Kracinovsky K, Cleveland H, Horne W, Franks J, Pociask D, Pilarski M, Alcorn JF, Chen K, Kolls JK. Murine models of Pneumocystis infection recapitulate human primary immune disorders. JCI Insight. 2018 Jun 21;3(12):e91894. doi: 10.1172/jci.insight.91894. PMID: 29925696; PMCID: PMC6124425.

Trevejo-Nunez G, Elsegeiny W, Aggor FEY, Tweedle JL, Kaplan Z, Gandhi P, Castillo P, Ferguson A, Alcorn JF, Chen K, Kolls JK, Gaffen SL. Interleukin-22 (IL-22) Binding Protein Constrains IL-22 Activity, Host Defense, and Oxidative Phosphorylation Genes during Pneumococcal Pneumonia. Infect Immun. 2019 Oct 18;87(11):e00550-19. doi: 10.1128/IAI.00550-19. PMID: 31451621; PMCID: PMC6803344.

Castillo-Dela Cruz P, Wanek AG, Kumar P, An X, Elsegeiny W, Horne W, Fitch A, Burr AHP, Gopalakrishna KP, Chen K, Methé BA, Canna SW, Hand TW, Kolls JK. Intestinal IL-17R Signaling Constrains IL-18-Driven Liver Inflammation by the Regulation of Microbiome-Derived Products. Cell Rep. 2019 Nov 19;29(8):2270-2283.e7. doi: 10.1016/j.celrep.2019.10.042. PMID: 31747600; PMCID: PMC6886715.

Castillo, P.A.C. & Hand, T.W. A little fiber goes a long way. Immunity. 2018, May; 48(5): 844-846.

Trainee: Past
Faculty Member: Adam Straub, PhD
Publications:

Dosunmu-Ogunbi AM, Wood KC, Novelli EM, Straub AC. Decoding the role of SOD2 in sickle cell disease. Blood Advances. 2019 Sep;3(17):2679-2687. DOI: 10.1182/bloodadvances.2019000527.