Publications

Trainee: Current

Faculty Member: Pal Monga, MD

Publications:

Lehrich BM, Tao J, Liu S, Hirsch TZ, Yasaka TM, Cao C, Delgado ER, Guan X, Lu S, Pan L, Liu Y, Singh S, Poddar M, Bell A, Singhi AD, Zucman-Rossi J, Wang Y, Monga SP, Development of Mutated β-catenin Gene Signature to identify CTNNB1 mutations from whole and spatial transcriptomic data in patients with HCC, JHEP Reports, https://doi.org/10.1016/j.jhepr.2024.101186.

Trainee Name: Andrew Liu

Trainee: Current

Faculty Member: Daniel Kaplan, MD, PhD

Publications:

Cohen JA, Edwards TN, Liu AW, Hirai T, Jones MR, Wu J, Li Y, Zhang S, Ho J, Davis BM, Albers KM, Kaplan DH. Cutaneous TRPV1+ Neurons Trigger Protective Innate Type 17 Anticipatory Immunity. Cell. 2019 Aug 8;178(4):919-932.e14. doi: 10.1016/j.cell.2019.06.022. Epub 2019 Jul 25. PMID: 31353219; PMCID: PMC6788801.

Kazi R, Evankovich MR, Liu R, Liu A, Moorhead A, Ferris LK, Falo LD Jr, English JC 3rd. Utilization of Asynchronous and Synchronous Teledermatology in a Large Health Care System During the COVID-19 Pandemic. Telemed J E Health. 2021 Jul;27(7):771-777. doi: 10.1089/tmj.2020.0299. Epub 2020 Oct 19. PMID: 33074786.

Liu AW, Gillis JE, Sumpter TL, Kaplan DH. Neuroimmune interactions in atopic and allergic contact dermatitis. J Allergy Clin Immunol. 2023 May;151(5):1169-1177. doi: 10.1016/j.jaci.2023.03.013. PMID: 37149370; PMCID: PMC10167546.

Trainee Name: Varun Mandi

Trainee: Current

Faculty Member: Vijay Yechoor, PhD

Publications:

Espinosa-Diez C, Mandi V, Du M, Liu M, Gomez D. Smooth muscle cells in atherosclerosis: clones but not carbon copies. JVS Vasc Sci. 2021;2:136-148. Published 2021 May 15. doi:10.1016/j.jvssci.2021.02.002

Trainee Name: Philip Mannes PhD

Trainee: Current

Faculty Member: Sina Tavakoli, MD, PhD

Publications:

Mannes PZ, Adams TS, Farsijani S, Barnes CE, Latoche JD, Day KE, Nedrow JR, Ahangari F, Kaminski N, Lee JS, Tavakoli S. Noninvasive assessment of the lung inflammation-fibrosis axis by targeted imaging of CMKLR1. Sci Adv. 2024 Jun 21;10(25):eadm9817. doi: 10.1126/sciadv.adm9817. Epub 2024 Jun 19. PMID: 38896611; PMCID: PMC11186491.

Zhu Q, Barnes CE, Mannes PZ, Latoche JD, Day KE, Nedrow JR, Novelli EM, Anderson CJ, Tavakoli S. Targeted imaging of very late antigen-4 for noninvasive assessment of lung inflammation-fibrosis axis. EJNMMI Res. 2023 Jun 5;13(1):55. doi: 10.1186/s13550-023-01006-0. PMID: 37273103; PMCID: PMC10240482.

Mannes PZ, Barnes CE, Latoche JD, Day KE, Nedrow JR, Lee JS, Tavakoli S. 2-deoxy-2-[¹⁸F]fluoro-D-glucose Positron Emission Tomography to Monitor Lung Inflammation and Therapeutic Response to Dexamethasone in a Murine Model of Acute Lung Injury. Mol Imaging Biol. 2023 Aug;25(4):681-691. doi: 10.1007/s11307-023-01813-w. Epub 2023 Mar 20. PMID: 36941514; PMCID: PMC10027262.

Mannes PZ, Barnes CE, Biermann J, Latoche JD, Day KE, Zhu Q, Tabary M, Xiong Z, Nedrow JR, Izar B, Anderson CJ, Villanueva FS, Lee JS, Tavakoli S. Molecular imaging of chemokine-like receptor 1 (CMKLR1) in experimental acute lung injury. Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2216458120. doi: 10.1073/pnas.2216458120. Epub 2023 Jan 10. PMID: 36626557; PMCID: PMC9934297.

Mannes PZ, Tavakoli S. Imaging Immunometabolism in Atherosclerosis. J Nucl Med. 2021 Jul 1;62(7):896-902. doi: 10.2967/jnumed.120.245407. Epub 2021 May 7. PMID: 33963045; PMCID: PMC8882876.

Mannes PZ, Wang TL, Ma W, Selzer J, Blanco C. Student Substance Use Policies in US Allopathic Medical Schools: A National Study. JAMA Psychiatry. 2021 Dec 1;78(12):1393-1395. doi: 10.1001/jamapsychiatry.2021.2666. PMID: 34586347; PMCID: PMC8482301.

Demirdelen S, Mannes PZ, Aral AM, Haddad J, Leers SA, Gomez D, Tavakoli S. Divergence of acetate uptake in proinflammatory and inflammation-resolving macrophages: implications for imaging atherosclerosis. J Nucl Cardiol. 2021. Epub 2021/01/10. doi: 10.1007/s12350-020-02479-5. PubMed PMID: 33420659.

Wagner S , Sudhamalla B , Mannes P, Sappa S , Kavoosi S , Dey D , Wang S , Islam K . Engineering bromodomains with a photoactive amino acid by engaging 'Privileged' tRNA synthetases. Chem Commun (Camb). 2020 Mar 28;56(25):3641-3644. doi: 10.1039/c9cc09891g. Epub 2020 Feb 28. PMID: 32107512; PMCID: PMC7146825.

Trainee Name: Ugonna Mbaekwe

Trainee: Current

Faculty Member: Corrine Kliment, MD, PhD

Publications:

Sui J, Xiao H, Mbaekwe U, Ting NC, Murday K, Hu Q, Gregory AD, Kapellos TS, Yildirim AÖ, Königshoff M, Zhang Y, Sciurba FC, Das J, Kliment CR. Interpretable machine learning uncovers epithelial transcriptional rewiring and a role for Gelsolin in COPD. JCI Insight. 2024 Oct 1:e180239. doi: 10.1172/jci.insight.180239. Epub ahead of print. PMID: 39352744.

Trainee Name: Amir Mina, PhD

Trainee: Current

Faculty Member: Shyam Visweswaran, MD, PhD

Publications:

Melachuri SR, Melachuri MK, Mina A, Anetakis K, Crammond DJ, Balzer JR, Shandal V, Thirumala PD. Optimal "Low" Pedicle Screw Stimulation Threshold to Predict New Postoperative Lower-Extremity Neurologic Deficits During Lumbar Spinal Fusions. World Neurosurg. 2021 Jul;151:e250-e256. doi: 10.1016/j.wneu.2021.04.022. Epub 2021 Apr 16. PMID: 33872842.

Moehl K, Shandal V, Anetakis K, Paras S, Mina A, Crammond D, Balzer J, Thirumala PD. Predicting transient ischemic attack after carotid endarterectomy: The role of intraoperative neurophysiological monitoring. Clin Neurophysiol. 2022 Sep;141:1-8. doi: 10.1016/j.clinph.2022.06.010. Epub 2022 Jun 24. PMID: 35797873.

Paras S, Mina A, Crammond DJ, Visweswaran S, Anetakis KM, Balzer JR, Shandal V, Thirumala PD. Cardiovascular-related mortality after intraoperative neurophysiologic monitoring changes during carotid endarterectomy. Clin Neurophysiol. 2022 Jul;139:43-48. doi: 10.1016/j.clinph.2022.04.005. Epub 2022 Apr 22. PMID: 35525076.

Fleseriu CM, Sultan I, Brown JA, Mina A, Frenchman J, Crammond DJ, Balzer J, Anetakis KM, Subramaniam K, Shandal V, Navid F, Thirumala PD. Role of Intraoperative Neurophysiological Monitoring in Preventing Stroke After Cardiac Surgery. Ann Thorac Surg. 2023 Sep;116(3):623-629. doi: 10.1016/j.athoracsur.2023.01.004. Epub 2023 Jan 10. PMID: 36634835.

Bata A, Al Qudah A, Algarni S, Al Ta'ani O, Balzer JR, Crammond DJ, Shandal V, Gross BA, Lang MJ, Anetakis KM, Narayanan S, Mina A, Thirumala PD. Diagnostic Accuracy of Somatosensory Evoked Potentials and Electroencephalography During Endovascular Treatment of Unruptured Cerebral Aneurysms. World Neurosurg. 2023 Jun 26:S1878-8750(23)00863-X. doi: 10.1016/j.wneu.2023.06.087. Epub ahead of print. PMID: 37380051.

Mina AI, Espino JU, Bradley AM, Thirumala PD, Batmanghelich K, Visweswaran S. Detecting Cerebral Ischemia From Electroencephalography During Carotid Endarterectomy Using Machine Learning. AMIA Jt Summits Transl Sci Proc. 2024 May 31;2024:613-622. PMID: 38827046; PMCID: PMC11141851.

Mina AI, Espino JU, Bradley AM, Thirumala P, Batmanghelich K, Visweswaran S. Time-Series Aware Metrics for the Evaluation of Intraoperative Electroencephalography-Based Ischemia Detection. Stud Health Technol Inform. 2024 Jan 25;310:274-278. doi: 10.3233/SHTI230970. PMID: 38269808.

Trainee Name: Robert Morrison

Trainee: Current

Faculty Member: Hassane Zarour, MD

Publications:

Davar D, Dzutsev AK, McCulloch JA, Rodrigues RR, Chauvin JM, Morrison RM, Deblasio RN, Menna C, Ding Q, Pagliano O, Zidi B, Zhang S, Badger JH, Vetizou M, Cole AM, Fernandes MR, Prescott S, Costa RGF, Balaji AK, Morgun A, Vujkovic-Cvijin I, Wang H, Borhani AA, Schwartz MB, Dubner HM, Ernst SJ, Rose A, Najjar YG, Belkaid Y, Kirkwood JM, Trinchieri G, Zarour HM. Fecal microbiota transplant overcomes resistance to anti-PD-1 therapy in melanoma patients. Science. 2021 Feb 5;371(6529):595-602. doi: 10.1126/science.abf3363. PMID: 33542131; PMCID: PMC8097968.

Bai Y, Qin Y, Fan Z, Morrison RM, Nam K, Zarour HM, Koldamova R, Padiath QS, Kim S, Park HJ. scMAPA: Identification of cell-type-specific alternative polyadenylation in complex tissues. Gigascience. 2022 Apr 30;11:giac033. doi: 10.1093/gigascience/giac033. PMID: 35488860; PMCID: PMC9055853.

Trainee Name: Ananya Mukundan PhD

Trainee: Current

Faculty Member: Andrew Hinck, PhD

Publications:

van Dinther M, Cunningham KT, Singh SP, White MPJ, Campion T, Ciancia C, van Veelen PA, de Ru AH, González-Prieto R, Mukundan A, Byeon CH, Staggers SR, Hinck CS, Hinck AP, Dijke PT, Maizels RM. CD44 acts as a coreceptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-β mimic. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2302370120. doi: 10.1073/pnas.2302370120. Epub 2023 Aug 17. PMID: 37590410; PMCID: PMC10450677.

Singh SP, Smyth DJ, Cunningham K, Mukundan A, Byeon CH, Hinck CS, White MPJ, Ciancia C, Wosowska N, Sanders A, Jin R, Lilla S, Zanivan S, Schoenherr C, Inman G, van Dinther M, Ten Dijke P, Hinck AP, Maizels RM. The helminth TGF-β mimic TGM4 is a modular ligand that binds CD44, CD49d and TGF-β receptors to preferentially target myeloid cells. bioRxiv [Preprint]. 2023 Nov 15:2023.11.13.566701. doi: 10.1101/2023.11.13.566701. PMID: 38014296; PMCID: PMC10680678.

Mukundan A, Byeon CH, Hinck CS, Cunningham K, Campion T, Smyth DJ, Maizels RM, Hinck AP. Convergent evolution of a parasite-encoded complement control protein-scaffold to mimic binding of mammalian TGF-β to its receptors, TβRI and TβRII. J Biol Chem. 2022 Jun;298(6):101994. doi: 10.1016/j.jbc.2022.101994. Epub 2022 Apr 29. PMID: 35500648; PMCID: PMC9163516.

McManus CM, Bouchery T, Suleiman M, Kildemoes AO, Ferguson A, Wang T, Finlay CM, Chan R, Renahan T, Mukundan A, Nkurunungi G, Bobardt SD. Hydra 2022: return of the interactive conference on helminth parasitology after the pandemic. Trends Parasitol. 2022 Dec;38(12):999-1007. doi: 10.1016/j.pt.2022.09.013. Epub 2022 Nov 2. PMID: 36335007.

Trainee Name: Shruti Nanivadekar

Trainee: Current

Faculty Member: Aryn Gittis, PhD

Publications:

Spix TA, Nanivadekar S, Toong N, Kaplow IM, Isett BR, Goksen Y, Pfenning AR, Gittis AH. Population-specific neuromodulation prolongs therapeutic benefits of deep brain stimulation. Science. 2021 Oct 8;374(6564):201-206. doi: 10.1126/science.abi7852. Epub 2021 Oct 7. PMID: 34618556.

Kariv S, Choi JW, Mirpour K, Gordon AM, Alijanpourotaghsara A, Benam M, Abdalla R, Chilukuri S, Gu JW, Bokil H, Nanivadekar S, Gittis AH, Pouratian N. Pilot Study of Acute Behavioral Effects of Pallidal Burst Stimulation in Parkinson's Disease. Mov Disord. 2024 Jul 15. doi: 10.1002/mds.29928. Epub ahead of print. PMID: 39007445.

Trainee Name: Hector Nieves-Rosado PhD

Trainee: Current

Faculty Member: Lawrence Kane, PhD

Publications:

Banerjee, H., Nieves-Rosado, HM, Kulkarni, A., Murter, B., McGrath, K. V., Chandran, U. R., . . . Kane, LP. Expression of Tim-3 drives phenotypic and functional changes in Treg cells in secondary lymphoid organs and the tumor microenvironment. Cell Rep; 2021. (PMID 34525351).

Nieves-Rosado HM., Jacobs JL., Naqvi A., Mellors JW., Macatangay BJC., Kane LP. TIM-3 signaling contributes to the suppressive capacity of Tregs from people with HIV on antiretroviral therapy. J Leukoc Biol; 2023. (PMID: 37350502).

Nieves-Rosado, HM., Banerjee, H., Gocher-Demske, A., Manandhar, P., Mehta, I., Ezenwa, O., Xie, B., Murter, B., Das, J., Vignali, DAA., Delgoffe, GM., Kane, LP. Tim-3 is required for Treg-mediated promotion of T cell exhaustion and viral persistence during chronic LCMV infection. Journal of Immunology; 2024.

Peralta, RM., Xie, B., Lontos, K., Nieves-Rosado, HM., Spahr, K., Ford, RB., Quann, K., Frisch, A., Dean, V., Philbin, M., Cillo, AR., Gingras, S., Poholek, AC., Kane, LP., Rivadeneira, DB., Delgoffe GM. Dysfunction of exhausted T cells is enforced by MCT11-mediated lactate metabolism. Nat. Immunol; 2024.