Publications

Trainee: Current

Faculty Member: Karl Kandler, PhD , Srivatsun Sadagopan, PhD

Publications:

Reitz, KM, Terhorst, L, Smith, CN, Campwala, IK, Owoc, MS, Downs-Canner, SM, Diego, EJ, Switzer, GE, Rosengart, MR, Myers, SP. Healthcare providers’ perceived support from their organization is associated with lower burnout and anxiety amid the COVID-19 pandemic. Plos One. 2021 Nov 19. PMID: 34797847, PMCID: PMC8604356

Baddour K, Fadel M, Zhao M, Corcoran M, Owoc MS, Thomas TH, Sabik LM, Nilsen ML, Ferris RL, Mady LJ. The cost of cure: Examining objective and subjective financial toxicity in head and neck cancer survivors. Head Neck. 2021 Jul 8. PMID: 34235804

Mady LJ, Lyu L, Owoc MS, Peddada SD, Thomas TH, Sabik LM, Johnson JT, Nilsen ML. Understanding financial toxicity in head and neck cancer survivors. Oral Oncology. 2019 Aug. PMID: 31345389

Trainee Name: Olivia Parks PhD

Trainee: Current

Faculty Member: John Williams, MD

Publications:

Mihi B, Gong Q, Nolan LS, Gale SE, Goree M, Hu E, Lanik WE, Rimer JM, Liu V, Parks OB, Lewis AN, Agrawal P, Laury ML, Kumar P, Huang E, Bidani SS, Luke CJ, Kolls JK, Good M. Interleukin-22 signaling attenuates necrotizing enterocolitis by promoting epithelial cell regeneration. Cell Rep Med. 2021 Jun 15;2(6):100320. doi: 10.1016/j.xcrm.2021.100320. PMID: 34195684; PMCID: PMC8233697.

Eddens T, Parks OB, Williams JV. Neonatal Immune Responses to Respiratory Viruses. Front Immunol. 2022 Apr 14;13:863149. doi: 10.3389/fimmu.2022.863149. PMID: 35493465; PMCID: PMC9047724.

Lin X, Gaudino SJ, Jang KK, Bahadur T, Singh A, Banerjee A, Beaupre M, Chu T, Wong HT, Kim CK, Kempen C, Axelrad J, Huang H, Khalid S, Shah V, Eskiocak O, Parks OB, Berisha A, McAleer JP, Good M, Hoshino M, Blumberg R, Bialkowska AB, Gaffen SL, Kolls JK, Yang VW, Beyaz S, Cadwell K, Kumar P. IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment. Immunity. 2022 Feb 8;55(2):237-253.e8. doi: 10.1016/j.immuni.2021.12.016. Epub 2022 Jan 25. PMID: 35081371; PMCID: PMC8895883.

Parks OB, Keith M, Squires JH, Venkat VL, Mahmood B. Liver Microabscesses in a Premature Neonate With Eosinophilic Colitis. ACG Case Rep J. 2022 Jul 1;9(7):e00817. doi: 10.14309/crj.0000000000000817. PMID: 35784499; PMCID: PMC9246066.

Freeman KG, Robotham AC, Parks OB, Abad L, Jacobs-Sera D, Lauer MJ, Podgorski JM, Zhang Y, Williams JV, White SJ, Kelly JF, Hatfull GF, Pope WH. Virion glycosylation influences mycobacteriophage immune recognition. Cell Host Microbe. 2023 Jul 12;31(7):1216-1231.e6. doi: 10.1016/j.chom.2023.05.028. Epub 2023 Jun 16. PMID: 37329881; PMCID: PMC10527164.

Parks OB, Eddens T, Sojati J, Lan J, Zhang Y, Oury TD, Ramsey M, Erickson JJ, Byersdorfer CA, Williams JV. Terminally exhausted CD8⁺ T cells contribute to age-dependent severity of respiratory virus infection. Immun Ageing. 2023 Aug 1;20(1):40. doi: 10.1186/s12979-023-00365-5. PMID: 37528458; PMCID: PMC10391960.

Sojati J, Parks OB, Zhang Y, Walters S, Lan J, Eddens T, Lou D, Fan L, Chen K, Oury TD, Williams JV. IFN-λ drives distinct lung immune landscape changes and antiviral responses in human metapneumovirus infection. mBio. 2024 May 8;15(5):e0055024. doi: 10.1128/mbio.00550-24. Epub 2024 Mar 26. PMID: 38530032; PMCID: PMC11077986.

Eddens T, Parks OB, Lou D, Fan L, Sojati J, Ramsey MJ, Schmitt L, Salgado CM, Reyes-Mugica M, Evans A, Zou HM, Oury TD, Byersdorfer C, Chen K, Williams JV. Monocyte Production of C1q Potentiates CD8⁺ T-Cell Function Following Respiratory Viral Infection. Am J Respir Cell Mol Biol. 2024 Sep;71(3):294-306. doi: 10.1165/rcmb.2024-0004OC. PMID: 38696270; PMCID: PMC11376238.

Trainee Name: BaDoi Phan PhD

Trainee: Current

Faculty Member: Andreas Pfenning, PhD

Publications:

Ramamurthy E, Agarwal S, Toong N, Sestili H, Kaplow IM, Chen Z, Phan B, Pfenning AR. Regression convolutional neural network models implicate peripheral immune regulatory variants in the predisposition to Alzheimer's disease. PLoS Comput Biol. 2024 Aug 26;20(8):e1012356. doi: 10.1371/journal.pcbi.1012356. PMID: 39186798; PMCID: PMC11389932.

Wirthlin ME, Schmid TA, Elie JE, Zhang X, Kowalczyk A, Redlich R, Shvareva VA, Rakuljic A, Ji MB, Bhat NS, Kaplow IM, Schäffer DE, Lawler AJ, Wang AZ, Phan BN, Annaldasula S, Brown AR, Lu T, Lim BK, Azim E; Zoonomia Consortium; Clark NL, Meyer WK, Pond SLK, Chikina M, Yartsev MM, Pfenning AR, Andrews G, Armstrong JC, Bianchi M, Birren BW, Bredemeyer KR, Breit AM, Christmas MJ, Clawson H, Damas J, Di Palma F, Diekhans M, Dong MX, Eizirik E, Fan K, Fanter C, Foley NM, Forsberg-Nilsson K, Garcia CJ, Gatesy J, Gazal S, Genereux DP, Goodman L, Grimshaw J, Halsey MK, Harris AJ, Hickey G, Hiller M, Hindle AG, Hubley RM, Hughes GM, Johnson J, Juan D, Kaplow IM, Karlsson EK, Keough KC, Kirilenko B, Koepfli KP, Korstian JM, Kowalczyk A, Kozyrev SV, Lawler AJ, Lawless C, Lehmann T, Levesque DL, Lewin HA, Li X, Lind A, Lindblad-Toh K, Mackay-Smith A, Marinescu VD, Marques-Bonet T, Mason VC, Meadows JRS, Meyer WK, Moore JE, Moreira LR, Moreno-Santillan DD, Morrill KM, Muntané G, Murphy WJ, Navarro A, Nweeia M, Ortmann S, Osmanski A, Paten B, Paulat NS, Pfenning AR, Phan BN, Pollard KS, Pratt HE, Ray DA, Reilly SK, Rosen JR, Ruf I, Ryan L, Ryder OA, Sabeti PC, Schäffer DE, Serres A, Shapiro B, Smit AFA, Springer M, Srinivasan C, Steiner C, Storer JM, Sullivan KAM, Sullivan PF, Sundström E, Supple MA, Swofford R, Talbot JE, Teeling E, Turner-Maier J, Valenzuela A, Wagner F, Wallerman O, Wang C, Wang J, Weng Z, Wilder AP, Wirthlin ME, Xue JR, Zhang X. Vocal learning-associated convergent evolution in mammalian proteins and regulatory elements. Science. 2024 Mar 29;383(6690):eabn3263. doi: 10.1126/science.abn3263. Epub 2024 Mar 29. PMID: 38422184; PMCID: PMC11313673.

Phan BN, Ray MH, Xue X, Fu C, Fenster RJ, Kohut SJ, Bergman J, Haber SN, McCullough KM, Fish MK, Glausier JR, Su Q, Tipton AE, Lewis DA, Freyberg Z, Tseng GC, Russek SJ, Alekseyev Y, Ressler KJ, Seney ML, Pfenning AR, Logan RW. Single nuclei transcriptomics in human and non-human primate striatum in opioid use disorder. Nat Commun. 2024 Jan 31;15(1):878. doi: 10.1038/s41467-024-45165-7. PMID: 38296993; PMCID: PMC10831093.

Chen HY, Phan BN, Shim G, Hamersky GR, Sadowski N, O'Donnell TS, Sripathy SR, Bohlen JF, Pfenning AR, Maher BJ. Psychiatric risk gene Transcription Factor 4 (TCF4) regulates the density and connectivity of distinct inhibitory interneuron subtypes. Mol Psychiatry. 2023 Nov;28(11):4679-4692. doi: 10.1038/s41380-023-02248-z. Epub 2023 Sep 28. PMID: 37770578; PMCID: PMC11144438.

Gayden J, Puig S, Srinivasan C, Phan BN, Abdelhady G, Buck SA, Gamble MC, Tejeda HA, Dong Y, Pfenning AR, Logan RW, Freyberg Z. Integrative multi-dimensional characterization of striatal projection neuron heterogeneity in adult brain. bioRxiv [Preprint]. 2023 Oct 21:2023.05.04.539488. doi: 10.1101/2023.05.04.539488. PMID: 37205475; PMCID: PMC10187292.

Kaplow IM, Lawler AJ, Schäffer DE, Srinivasan C, Sestili HH, Wirthlin ME, Phan BN, Prasad K, Brown AR, Zhang X, Foley K, Genereux DP; Zoonomia Consortium**; Karlsson EK, Lindblad-Toh K, Meyer WK, Pfenning AR. Relating enhancer genetic variation across mammals to complex phenotypes using machine learning. Science. 2023 Apr 28;380(6643):eabm7993. doi: 10.1126/science.abm7993. Epub 2023 Apr 28. PMID: 37104615; PMCID: PMC10322212.

Sullivan PF, Meadows JRS, Gazal S, Phan BN, Li X, Genereux DP, Dong MX, Bianchi M, Andrews G, Sakthikumar S, Nordin J, Roy A, Christmas MJ, Marinescu VD, Wang C, Wallerman O, Xue J, Yao S, Sun Q, Szatkiewicz J, Wen J, Huckins LM, Lawler A, Keough KC, Zheng Z, Zeng J, Wray NR, Li Y, Johnson J, Chen J; Zoonomia Consortium§; Paten B, Reilly SK, Hughes GM, Weng Z, Pollard KS, Pfenning AR, Forsberg-Nilsson K, Karlsson EK, Lindblad-Toh K. Leveraging base-pair mammalian constraint to understand genetic variation and human disease. Science. 2023 Apr 28;380(6643):eabn2937. doi: 10.1126/science.abn2937. Epub 2023 Apr 28. PMID: 37104612; PMCID: PMC10259825.

Christmas MJ, Kaplow IM, Genereux DP, Dong MX, Hughes GM, Li X, Sullivan PF, Hindle AG, Andrews G, Armstrong JC, Bianchi M, Breit AM, Diekhans M, Fanter C, Foley NM, Goodman DB, Goodman L, Keough KC, Kirilenko B, Kowalczyk A, Lawless C, Lind AL, Meadows JRS, Moreira LR, Redlich RW, Ryan L, Swofford R, Valenzuela A, Wagner F, Wallerman O, Brown AR, Damas J, Fan K, Gatesy J, Grimshaw J, Johnson J, Kozyrev SV, Lawler AJ, Marinescu VD, Morrill KM, Osmanski A, Paulat NS, Phan BN, Reilly SK, Schäffer DE, Steiner C, Supple MA, Wilder AP, Wirthlin ME, Xue JR; Zoonomia Consortium§; Birren BW, Gazal S, Hubley RM, Koepfli KP, Marques-Bonet T, Meyer WK, Nweeia M, Sabeti PC, Shapiro B, Smit AFA, Springer MS, Teeling EC, Weng Z, Hiller M, Levesque DL, Lewin HA, Murphy WJ, Navarro A, Paten B, Pollard KS, Ray DA, Ruf I, Ryder OA, Pfenning AR, Lindblad-Toh K, Karlsson EK. Evolutionary constraint and innovation across hundreds of placental mammals. Science. 2023 Apr 28;380(6643):eabn3943. doi: 10.1126/science.abn3943. Epub 2023 Apr 28. PMID: 37104599; PMCID: PMC10250106.

Sullivan PF, Meadows JRS, Gazal S, Phan BN, Li X, Genereux DP, Dong MX, Bianchi M, Andrews G, Sakthikumar S, Nordin J, Roy A, Christmas MJ, Marinescu VD, Wallerman O, Xue JR, Li Y, Yao S, Sun Q, Szatkiewicz J, Wen J, Huckins LM, Lawler AJ, Keough KC, Zheng Z, Zeng J, Wray NR, Johnson J, Chen J; Zoonomia Consortium; Paten B, Reilly SK, Hughes GM, Weng Z, Pollard KS, Pfenning AR, Forsberg-Nilsson K, Karlsson EK, Lindblad-Toh K. Leveraging Base Pair Mammalian Constraint to Understand Genetic Variation and Human Disease. bioRxiv [Preprint]. 2023 Mar 10:2023.03.10.531987. doi: 10.1101/2023.03.10.531987. Update in: Science. 2023 Apr 28;380(6643):eabn2937. doi: 10.1126/science.abn2937. PMID: 36945512; PMCID: PMC10028973.

Desai DD, Yu SE, Salvatore B, Goldberg Z, Bowers EMR, Moore JA, Phan B, Lee SE. Olfactory and neurological outcomes of SARS-CoV-2 from acute infection to recovery. Front Allergy. 2022 Oct 26;3:1019274. doi: 10.3389/falgy.2022.1019274. PMID: 36389036; PMCID: PMC9644087.

Lawler AJ, Ramamurthy E, Brown AR, Shin N, Kim Y, Toong N, Kaplow IM, Wirthlin M, Zhang X, Phan BN, Fox GA, Wade K, He J, Ozturk BE, Byrne LC, Stauffer WR, Fish KN, Pfenning AR. Machine learning sequence prioritization for cell type-specific enhancer design. Elife. 2022 May 16;11:e69571. doi: 10.7554/eLife.69571. PMID: 35576146; PMCID: PMC9110026.

Morris J, Olonisakin TF, Moore JA, Phan B, Parker DM, Uribe BA, Barel SJ, Bowers EMR, Buchheit KM, Laidlaw TM, Lee SE. Inhibiting the type 2 inflammatory pathway with dupilumab is associated with an increase in interleukin-4 and interleukin-18 production. Int Forum Allergy Rhinol. 2022 Oct;12(10):1313-1316. doi: 10.1002/alr.23003. Epub 2022 Apr 29. PMID: 35394682.

Xue X, Zong W, Glausier JR, Kim SM, Shelton MA, Phan BN, Srinivasan C, Pfenning AR, Tseng GC, Lewis DA, Seney ML, Logan RW. Molecular rhythm alterations in prefrontal cortex and nucleus accumbens associated with opioid use disorder. Transl Psychiatry. 2022 Mar 26;12(1):123. doi: 10.1038/s41398-022-01894-1. PMID: 35347109; PMCID: PMC8960783.

Srinivasan C, Phan BN, Lawler AJ, Ramamurthy E, Kleyman M, Brown AR, Kaplow IM, Wirthlin ME, Pfenning AR. Addiction-associated genetic variants implicate brain cell type- and region-specific cis-regulatory elements in addiction neurobiology. J Neurosci. 2021 Aug 30:JN-RM-2534-20. doi: 10.1523/JNEUROSCI.2534-20.2021. Epub ahead of print. PMID: 34462306.

Phan, B.N., Bohlen, J.F., Davis, B.A. et al. A myelin-related transcriptomic profile is shared by Pitt–Hopkins syndrome models and human autism spectrum disorder. Nat Neurosci 23, 375–385 (2020). https://doi.org/10.1038/s41593-019-0578-x

Srinivasan C*, Phan BN*, Lawler AJ, Ramamurthy E, Kleyman M, Brown AR, Kaplow IM, Wirthlin ME, Pfenning AR. Addiction-associated genetic variants implicate brain cell type- and region-specific cis-regulatory elements in addiction neurobiology. bioRxiv 2020.09.29.318329; doi: https://doi.org/10.1101/2020.09.29.318329. In review

Seney ML, Moon-Kim S, Glausier JR, Hildebrand MA, XiangningXue, Zong W, Wang J, Shelton MA, Phan BN, Srinivasan C, Pfenning AR, Tseng GC, Lewis DA, Freyberg Z, Logan RW. Transcriptional alterations in opioid use disorder reveal an interplay between neuroinflammation and synaptic remodeling.bioRxiv 2020.09.14.296707; doi: https://doi.org/10.1101/2020.09.14.296707. In review

Phan BN, Bohlen JF, Davis BA, Ye Z, Chen HY, Mayfield B, Sripathy SR, Cerceo Page S, Campbell MN, Smith HL, Gallop D, Kim H, Thaxton CL, Simon JM, Burke EE, Shin JH, Kennedy AJ, Sweatt JD, Philpot BD, Jaffe AE, Maher BJ. A myelin-related transcriptomic profile is shared by Pitt-Hopkins syndrome models and human autism spectrum disorder. Nat Neurosci. 2020 Feb 3;. doi: 10.1038/s41593-019-0578-x. [Epub ahead of print] PubMed PMID: 32015540.

Burke EE, Chenoweth JG, Shin JH, Collado-Torres L, Kim SK, Micali N, Wang Y, Colantuoni C, Straub RE, Hoeppner DJ, Chen HY, Sellers A, Shibbani K, Hamersky GR, Diaz Bustamante M, Phan BN, Ulrich WS, Valencia C, Jaishankar A, Price AJ, Rajpurohit A, Semick SA, Bürli RW, Barrow JC, Hiler DJ, Page SC, Martinowich K, Hyde TM, Kleinman JE, Berman KF, Apud JA, Cross AJ, Brandon NJ, Weinberger DR, Maher BJ, McKay RDG, Jaffe AE. Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs. Nat Commun. 2020 Jan 23;11(1):462. doi: 10.1038/s41467-019-14266-z. PubMed PMID: 31974374; PubMed Central PMCID: PMC6978526.

Maynard KR, Tippani M, Takahashi Y, Phan BN, Hyde TM, Jaffe AE, Martinowich K. dotdotdot: an automated approach to quantify multiplex single molecule fluorescent in situ hybridization (smFISH) images in complex tissues. Nucleic Acids Research, Volume 48, Issue 11, 19 June 2020, Page e66, https://doi.org/10.1093/nar/gkaa312

Chen HC, Polisetty TS, Zhu K, Phan BN, Durr NJ, Tian J, Mahoney NR. A quantitative analysis of factors influencing lower lid retraction and involutional ectropion. J Plast Reconstr Aesthet Surg. 2019 Jan;72(1):137-171. doi: 10.1016/j.bjps.2018.10.020. Epub 2018 Nov 2. PubMed PMID: 30467002.

Perez JL, Ozpinar A, Kano H, Phan B, Niranjan A, Lunsford LD. Salvage Stereotactic Radiosurgery in Breast Cancer Patients with Multiple Brain Metastases. World Neurosurg. 2019 May;125:e479-e486. doi: 10.1016/j.wneu.2019.01.108. Epub 2019 Jan 31. PubMed PMID: 30710716.

Trainee Name: Tara Pirnia, PhD

Trainee: Current

Faculty Member: Leila Wehbe, Bonnie Nazbanou

Publications:

Lipski WJ, Alhourani A, Pirnia T, Jones PW, Dastolfo-Hromack C, Helou LB, Crammond DJ, Shaiman S, Dickey MW, Holt LL, Turner RS, Fiez JA, Richardson RM. Subthalamic Nucleus Neurons Differentially Encode Early and Late Aspects of Speech Production. J Neurosci. 2018 Jun 13;38(24):5620-5631. doi: 10.1523/JNEUROSCI.3480-17.2018. Epub 2018 May 22. PMID: 29789378; PMCID: PMC6001034.

Trainee Name: Rumana Rashid

Trainee: Current

Faculty Member: Michael Becich, MD, PhD

Publications:

Rashid R, Copelli S, Silverstein JC, Becich MJ. REDCap and the National Mesothelioma Virtual Bank-a scalable and sustainable model for rare disease biorepositories. J Am Med Inform Assoc. 2023 Jul 24:ocad132. doi: 10.1093/jamia/ocad132. Epub ahead of print. PMID: 37487555.

Trainee Name: Alexander Schuyler PhD

Trainee: Current

Faculty Member: Sally Wenzel, MD

Publications:

Schuyler AJ, Wenzel SE. Historical Redlining Impacts Contemporary Environmental and Asthma-related Outcomes in Black Adults. Am J Respir Crit Care Med. 2022 Oct 1;206(7):824-837. doi: 10.1164/rccm.202112-2707OC. PMID: 35612914; PMCID: PMC9799280.

Nagasaki T, Schuyler AJ, Zhao J, Samovich SN, Yamada K, Deng Y, Ginebaugh SP, Christenson SA, Woodruff PG, Fahy JV, Trudeau JB, Stoyanovsky D, Ray A, Tyurina YY, Kagan VE, Wenzel SE. 15LO1 dictates glutathione redox changes in asthmatic airway epithelium to worsen type 2 inflammation. J Clin Invest. 2022 Jan 4;132(1):e151685. doi: 10.1172/JCI151685. PMID: 34762602; PMCID: PMC8718153.

Trainee Name: Amy Sentis PhD

Trainee: Current

Faculty Member: Timothy Verstynen, PhD

Publications:

Sentis AI, Rasero J, Gianaros PJ, Verstynen TD. Cortical and subcortical brain networks predict prevailing heart rate. Psychophysiology. 2024 Jul 1:e14641. doi: 10.1111/psyp.14641. Epub ahead of print. PMID: 38951745.

Rasero J, Betzel R, Sentis AI, Kraynak TE, Gianaros PJ, Verstynen T. Similarity in evoked responses does not imply similarity in macroscopic network states. Netw Neurosci. 2024 Apr 1;8(1):335-354. doi: 10.1162/netn_a_00354. PMID: 38711543; PMCID: PMC11073549.

Rasero J, Verstynen TD, DuPont CM, Kraynak TE, Barinas-Mitchell E, Scudder MR, Kamarck TW, Sentis AI, Leckie RL, Gianaros PJ. Stressor-evoked brain activity, cardiovascular reactivity, and subclinical atherosclerosis in midlife adults. medRxiv [Preprint]. 2024 Feb 6:2024.02.05.24302236. doi: 10.1101/2024.02.05.24302236. PMID: 38370849; PMCID: PMC10871357.

Sentis AI, Rasero J, Gianaros PJ, Verstynen TD. Cortical and subcortical brain networks predict prevailing heart rate. bioRxiv [Preprint]. 2024 Jan 7:2023.09.23.559114. doi: 10.1101/2023.09.23.559114. Update in: Psychophysiology. 2024 Jul 1:e14641. doi: 10.1111/psyp.14641. PMID: 38260308; PMCID: PMC10802251.

Sentis AI, Rasero J, Gianaros PJ, Verstynen TD. Integrating multiple brain imaging modalities does not boost prediction of subclinical atherosclerosis in midlife adults. Neuroimage Clin. 2022;35:103134. doi: 10.1016/j.nicl.2022.103134. Epub 2022 Jul 29. PMID: 36002967; PMCID: PMC9421527.

Rasero J, Sentis AI, Yeh FC, Verstynen T. Integrating across neuroimaging modalities boosts prediction accuracy of cognitive ability. PLoS Comput Biol. 2021 Mar 5;17(3):e1008347. doi: 10.1371/journal.pcbi.1008347. PMID: 33667224; PMCID: PMC7984650.

Trainee Name: Claire Simmons

Trainee: Current

Faculty Member: Marlene Behrmann, PhD

Publications:

Claire Simmons, Michael C. Granovetter, Sophie Robert, Tina T. Liu, Christina Patterson, Marlene Behrmann, “Holistic processing and face expertise after pediatric resection of occipitotemporal cortex”, Neuropsychologia, 2024, 108789, ISSN 0028-3932, https://doi.org/10.1016/j.neuropsychologia.2024.108789.

Vladislav Ayzenberg, Claire Simmons, Marlene Behrmann, Temporal asymmetries and interactions between dorsal and ventral visual pathways during object recognition, Cerebral Cortex Communications, 2023;, tgad003, https://doi.org/10.1093/texcom/tgad003.

Krasich, K., Simmons, C., O’Neill, K. et al. Prestimulus oscillatory brain activity interacts with evoked recurrent processing to facilitate conscious visual perception. Sci Rep 12, 22126 (2022). https://doi.org/10.1038/s41598-022-25720-2

Simmons C, McKee P, Antonios I, Smith A, Sinnott-Armstrong W. Bad dream frequency predicts mental health needs during the SARS-CoV-2 pandemic. J Affect Disord Rep. 2022 Dec;10:100448. doi: 10.1016/j.jadr.2022.100448. Epub 2022 Nov 20. PMID: 36438981; PMCID: PMC9675936.

Trainee Name: Jorna Sojati PhD

Trainee: Current

Faculty Member: John Williams, MD

Publications:

Ortega-Gonzalez P, Taylor G, Jangra RK, Tenorio R, Fernandez de Castro I, Mainou BA, Orchard RC, Wilen CB, Brigleb PH, Sojati J, Chandran K, Sachse M, Risco C, Dermody TS. Reovirus infection is regulated by NPC1 and endosomal cholesterol homeostasis. PLoS Pathog. 2022 Mar 9;18(3):e1010322. doi: 10.1371/journal.ppat.1010322. PMID: 35263388; PMCID: PMC8906592.

Parks O.B., Eddens T.J., Sojati J., Lan J., Zhang Y., Oury T.D., Ramsey M.J., Erickson J.J., Byersdorfer C., Williams J.V. “Terminally exhausted CD8+ T cells contribute to age-dependent severity of respiratory virus infection. Immunity and Ageing 20, 40 (2023). https://doi.org/10.1186/s12979-023-00365-5

Sojati J, Murali A, Pressimone C, Dakroub A. A Cross-Sectional Factor Analysis of COVID-19 and Influenza Vaccination Decisions in a Racially Diverse Western Pennsylvania Community. J Prim Care Community Health. 2023 Jan-Dec;14:21501319231212287. doi: 10.1177/21501319231212287.

Murali A,* Sojati J,* Levochkina M, Pressimone C, Griffith K, Fan E, Dakroub A. A Cross-Sectional Analysis of Community Perceptions of Flu and COVID-19 Vaccines at Turtle Creek Primary Care Center. Community Health Equity Res Policy. 2023 Oct 14:2752535X231205665. doi: 10.1177/2752535X231205665.

Zhang Y, Xu J, Miranda-Katz M, Sojati J, Tollefson SJ, Manni ML, Alcorn JF, Sarkar SN, Williams JV. Distinct roles for type I and type III interferons in virulent human metapneumovirus pathogenesis. PLoS Pathog. 2024 Feb 5;20(2):e1011840. doi: 10.1371/journal.ppat.1011840.

Sojati J, Murali A, Rapsinski G, Williams JV. Do Not Throw Away Your Shot: Pilot Study in Improving Medical School Curricula Through Focused Vaccine Education. AJPM Focus. 2023 Dec 23;3(2):100178. doi: 10.1016/j.focus.2023.100178.

Sojati J, Zhang Y, Williams JV. Clinical human metapneumovirus isolates show distinct pathogenesis and inflammatory profiles but similar CD8+ T cell impairment. mSphere. 2024 Jan 30;9(1):e0057023. doi: 10.1128/msphere.00570-23. Epub 2024 Jan 10.

Sojati J, Parks OB, Zhang Y, Walters S, Lan J, Eddens T, Lou D, Fan L, Chen K, Oury TD, Williams JV. IFN-λ drives distinct lung immune landscape changes and antiviral responses in human metapneumovirus infection. mBio. 2024 May 8;15(5):e0055024. doi: 10.1128/mbio.00550-24. Epub 2024 Mar 26. PMID: 38530032; PMCID: PMC11077986.

Trainee Name: Justin Sui

Trainee: Current

Faculty Member: Corrine Kliment , MD, PhD

Publications:

Florentin J, O'Neil SP, Ohayon LL, Uddin A, Vasamsetti SB, Arunkumar A, Ghosh S, Boatz JC, Sui J, Kliment CR, Chan SY, Dutta P. VEGF Receptor 1 Promotes Hypoxia-Induced Hematopoietic Progenitor Proliferation and Differentiation. Front Immunol. 2022 May 12;13:882484. doi: 10.3389/fimmu.2022.882484. PMID: 35634304; PMCID: PMC9133347.

Sui J, Boatz JC, Shi J, Hu Q, Li X, Zhang Y, Königshoff M, Kliment CR. Loss of ANT1 Increases Fibrosis and Epithelial Cell Senescence in Idiopathic Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2023 Nov;69(5):556-569. doi: 10.1165/rcmb.2022-0315OC. PMID: 37487137; PMCID: PMC10633847.

Sui J, Kliment C. Reply to Kobayashi et al.: Adenine Nucleotide Translocases and Cellular Senescence in Idiopathic Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2024 Mar;70(3):226-227. doi: 10.1165/rcmb.2023-0405LE. PMID: 38128102; PMCID: PMC10914769.